Results 261 to 270 of about 4,355,944 (375)

KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.

Cancer Research, 2006
A. Lièvre, J. Bachet, D. Le Corre, V. Boige, B. Landi, J. Emile, J. Côté, G. Tomasic, C. Penna, M. Ducreux, P. Rougier, F. Penault-Llorca, P. Laurent-Puig   +12 more
semanticscholar   +1 more source

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

FEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu, Yumi Iwashita, Keisuke Tachibana, Itsuki Nishino, Yuki Niwa, Atsuko Uyeda, Kazuki Matsuo, Masahiro Nagahama, Masuo Kondoh   +8 more
wiley   +1 more source

To be or not to be a protein coding mutation, that's the question! [PDF]

NAR Genom Bioinform
De Groote D, Pepe D, Janssens X, De Keersmaecker K.   +3 more
europepmc   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

Deep Learning Predicts EGFR Mutation Status from Histology Images in Non-Small Cell Lung Cancer. [PDF]

Cancer Res Commun
Park J, Shin S, Hwang W, Keum S, Brattoli B, Rawson JH, Lee T, Pereira S, Ahn CH, Senior MJT, Qaiser T, Kim S, Kim H, Chung JH, Choi YL, Lee SH, Bannister H, Riboni-Verri E, Ock CY, Hill RJ, Ali S, Moore L.   +21 more
europepmc   +1 more source

In vitro susceptibility of Plasmodium falciparum isolates from the China-Myanmar border area to artemisinins and correlation with K13 mutations

, 2019
Jie Zhang, Na Li, Faiza Amber Siddiqui, Shiling Xu, Jinting Geng, Jiaqi Zhang, Xi He, Luyi Zhao, Liang Pi, Yanmei Zhang, Cuiying Li, Xi Chen, Yanrui Wu, Jun Miao, Yaming Cao, Liwang Cui, Zhaoqing Yang   +16 more
openalex   +1 more source

Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man.

New England Journal of Medicine, 1994
Eric P. Smith, J. Boyd, G. Frank, Hiroyuki Takahashi, R. M. Cohen, B. Specker, T. Williams, D. Lubahn, K. Korach   +8 more
semanticscholar   +1 more source

Determinate Mutation [PDF]

Science, 1905
openaire   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

A prospective, multicenter, comprehensive genomic profile signature study in patients with EGFR-mutant advanced non-small cell lung cancer at the first-line treatment failure of osimertinib. [PDF]

Signal Transduct Target Ther
Shi Y, Lv D, Feng W, Liu S, Xing P, Yu Y, Yin J, Ren X, Zhang J, Han G, Zhang Y, Cang S, Chen J, Chen E, Meng L, Zhang Y.   +15 more
europepmc   +1 more source