Results 271 to 280 of about 4,183,748 (324)

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

The heterozygous mutation <i>COL4A4</i> c.817-1G>A causes Alport syndrome in a Chinese family: a case report. [PDF]

Front Pediatr
Wang D, Li X, Cheng K, Zheng L, Yu P, Lai P.   +5 more
europepmc   +1 more source

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

FEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu, Lavinia Liliana Ruta, Claudia Valentina Popa, Simona Ghenea, Ileana Cornelia Farcasanu   +4 more
wiley   +1 more source

Ultraviolet Induced Mutations in Chlamydomonas moewusii Gerloff

, 1952
Ralph A. Lewin
openalex   +1 more source

Assessing Olfactory Acuity in Primary Ciliary Dyskinesia with the <i>RSPH4A</i> Founder Mutation. [PDF]

J Clin Med
De Jesús MA, De Jesús-Rojas W.
europepmc   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

CONTRIBUTION TO THE HISTORY OF A MUTATION DURING 1,000,000 YEARS

, 1955
Björn Kurtén
openalex   +1 more source

A Canine <i>c-kit</i> Novel Mutation Isolated from a Gastrointestinal Stromal Tumor (GIST) Retains the Ability to Form Dimers but Lacks Autophosphorylation. [PDF]

Animals (Basel)
Shimakawa K, Doge S, Michishita M, Tanabe E, Tajima T, Kobayashi M, Bonkobara M, Watanabe M, Ochiai K, Tanaka Y.   +9 more
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

City scale related to epidermal growth factor receptor mutations status in Chinese non-small cell lung cancer. [PDF]

Discov Oncol
Ding GG, Wen JL, Gong R, Yang JJ, Cen WJ, Deng L, Wang F, Sun LY.   +7 more
europepmc   +1 more source