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Expression of human MutS homolog 2 (hMSH2) protein in resting and proliferating cells.

Oncogene, 1996
The hMSH2 protein plays an important role in the DNA mismatch repair system. Since this system is involved in the correction of errors that occur during DNA replication, we studied the expression of hMSH2 protein in resting and DNA-replicating cells, as well as through the cell cycle in cell types with different growth characteristics.
Marra, Giancarlo   +5 more
openaire   +2 more sources

[Abnormal expression of fragile histidine triad (FHIT) and Mut S homolog 2 (MSH2) proteins in human sporadic colorectal carcinoma and their clinical significance].

Ai zheng = Aizheng = Chinese journal of cancer, 2004
Frequent loss of fragile histidine triad (FHIT) expression in human gastrointestinal tract carcinomas has been reported; however, there were divergent opinions regarding FHIT expression in colorectal carcinoma. Recent studies have suggested that FHIT inactivation can be a consequence of defects in mismatch repair proteins, particularly mut S homolog 2 (
Cheng-Cai, Yao   +2 more
openaire   +1 more source

Machine Learning-Based Pathomics Signature in Predicting MSH2 Expression and Prognosis in Gastric Cancer.

Clinical and Translational Gastroenterology
BACKGROUND Gastric cancer (GC) is one of the most prevalent and lethal gastrointestinal malignancies. MutS homolog 2 (MSH2), a DNA mismatch repair protein, has emerged as a promising prognostic biomarker. However, traditional histopathological evaluation
Zheng-Rong Zhang   +7 more
semanticscholar   +1 more source

Association of glutaminase expression with immune-suppressive tumor microenvironment, clinicopathologic features, and clinical outcomes in endometrial cancer

International Journal of Gynecological Cancer
Objective Increased glutamine metabolism by cancer cells via upregulation of the drug-targetable enzyme glutaminase may contribute to an immune-suppressive tumor microenvironment.
S. Asaka   +11 more
semanticscholar   +1 more source

Suppression of long noncoding RNA NCK1‐AS1 increases chemosensitivity to cisplatin in cervical cancer

Journal of Cellular Physiology, 2018
Cervical cancer remains a serious health problem till now, with nearly 500,000 women cases diagnosed each year around the world. Long noncoding RNA (lncRNA) is a novel class of RNA transcripts (>200 nucleotides in length) participating in gene ...
Wei-yi Zhang   +3 more
semanticscholar   +1 more source

The contemporary management of cancers of the sinonasal tract in adults

Ca-A Cancer Journal for Clinicians, 2023
Rajat Thawani
exaly  

Highly accurate protein structure prediction with AlphaFold

Nature, 2021
John M Jumper   +2 more
exaly  

MutS homolog 2 plays a role in Vγ9δ2 T cell-mediated anti-gastric carcinoma immunity

, 2014
代玉梅   +7 more
semanticscholar   +1 more source

The protein corona from nanomedicine to environmental science

Nature Reviews Materials, 2023
Assist Prof Morteza Mahmoudi   +2 more
exaly  

Immune profiling of pituitary tumors reveals variations in immune infiltration and checkpoint molecule expression

Pituitary, 2021
Yu Mei   +10 more
semanticscholar   +1 more source

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