Results 61 to 70 of about 5,026 (303)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Investigation of errors in microcontroller interface circuit for mutual inductance sensor

open access: yesEngineering Science and Technology, an International Journal, 2019
This paper proposes direct microcontroller interface circuit on Arduino platform, which is realized using the inductive sensors. The circuit is composed of two external resistors and two reference inductors resulting in four RL circuits.
A. Anarghya   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

THE DEVELOPMENT OF MUTUAL INDUCTANCE COMPUTATION TOOL FOR WIRELESS POWER TRANSFER

open access: yesGazi Üniversitesi Fen Bilimleri Dergisi, 2019
Wireless power transmission systems, which aim to eliminate cable complexity and the difference between the connection terminals of devices, are now widely used in many areas such as mobile phone, toothbrush, shaver and electric vehicles.
Orhan KAPLAN
doaj   +1 more source

Modeling and Design of a Transmission Coil and Four Cascaded Receiving Coils Wireless Charging Structure With Lateral Misalignments

open access: yesIEEE Access, 2020
Magnetic resonance wireless power transfer (WPT) is an emerging technology that may create new applications for wireless power charging. However, the mutual inductance fluctuations resulting from lateral misalignments are the major factors hindering the ...
Zhongqi Li, Jiliang Yi
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Mutual Inductance of Two Coplanar Rectangular Contours with Symmetrical Internal Arrangement

open access: yesИзвестия высших учебных заведений России: Радиоэлектроника, 2018
The expediency of developing expressions for mutual inductance of rectangular and square coplanar contours is caused by configuration of frame antennas typical for RFID-technologies.
G. N. Tsitsikian, A. I. Senchenko
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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