Results 71 to 80 of about 1,341,828 (286)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Analysis of mutual inductance effect between decoupling capacitors on planar power bus [PDF]
, 2010 The physics associated with mutual inductance between vias has been analyzed, and a method has been proposed to calculate the total equivalent inductance including the effect of mutual inductance.
Archambeault, Bruce +7 more
core +1 more source
Coupling Between Separate Phases of Coaxial Double Circuit Transmission Lines
Active and Passive Electronic Components, 1988 The paper studies the so-called coaxial overhead transmission lines. The concentric phases are considered. The mathematical analysis for voltage and current is presented.
M. Hamed
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
On the Flux Linkage between Pancake Coils in Resonance-Type Wireless Power Transfer Systems
International Journal of Antennas and Propagation, 2020 This work presents a series representation for the mutual inductance of two coaxial pancake coils which remains accurate in non-quasi-static regime under the hypothesis that the current in the source coil is uniformly distributed.
Mauro Parise +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Comparative Evaluation of the Air Core Magnetic Design for MHz+ Switching Frequency
Applied SciencesPower electronics with a possible novel distributed system pose fresh challenges and require continuous improvement. One approach is to increase the switching frequency, thereby reducing size and weight.
Oleksandr Matiushkin +5 more
doaj +1 more source
Energies, 2018 Square and circular coils are two typical topologies for coupling coils and are applied to wireless charging. However, most of the research on coupling coils is based on the finite element model (FEM), which is a time-consuming process for 3-D structure ...
Zhichao Luo, Xuezhe Wei
doaj +1 more source