Results 51 to 60 of about 20,567 (255)

Entanglement wedge minimum cross-section in holographic massive gravity theory

open access: yesJournal of High Energy Physics, 2021
We study the entanglement wedge cross-section (EWCS) in holographic massive gravity theory, in which a first and second-order phase transition can occur.
Peng Liu   +3 more
doaj   +1 more source

Information Bottleneck Theory Based Exploration of Cascade Learning

open access: yesEntropy, 2021
In solving challenging pattern recognition problems, deep neural networks have shown excellent performance by forming powerful mappings between inputs and targets, learning representations (features) and making subsequent predictions.
Xin Du   +2 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

On Normalized Mutual Information: Measure Derivations and Properties

open access: yesEntropy, 2017
Starting with a new formulation for the mutual information (MI) between a pair of events, this paper derives alternative upper bounds and extends those to the case of two discrete random variables.
Tarald O. Kvålseth
doaj   +1 more source

ennemi: Non-linear correlation detection with mutual information

open access: yesSoftwareX, 2021
We present ennemi, a Python package for correlation analysis based on mutual information (MI). MI is a measure of relationship between variables. Unlike Pearson correlation it is valid also for non-linear relationships, yet in the linear case the two are
Petri Laarne   +2 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

T-value and mutual information as measures of the association strength in Serbian language [PDF]

open access: yesPsihologija, 2006
Since the study of Meyer and Schvaneveldt (1971), a large number of researches have shown facilitation effect in cognitive processing of a given word when it is preceded by a semantically (i.e. associatively) related word.
Lisac Jelena, Milin Petar
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Detection of Respiration Movement Asymmetry Between the Left and Right Lungs Using Mutual Information and Transfer Entropy

open access: yesIEEE Access, 2018
Using diagnostic imaging, asymmetry in the mechanic of the left and right lungs has been discovered in unilateral lung disease. Unilateral lung disease might affect information interaction between two lungs, which is often neglected in the study of lung ...
Lianrong Zheng   +5 more
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

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