Results 71 to 80 of about 401,065 (270)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Bounds on the Excess Minimum Risk via Generalized Information Divergence Measures

Entropy
Given finite-dimensional random vectors Y, X, and Z that form a Markov chain in that order (Y→X→Z), we derive the upper bounds on the excess minimum risk using generalized information divergence measures.
Ananya Omanwar, Fady Alajaji, Tamás Linder   +2 more
doaj   +1 more source

A New Mutual Information based Similarity Measure for Medical Image Registration [PDF]

, 2012
Medical image registration (IR) is the systematic process of aligning spate images, often involving different modalities with common reference framework, so complementary information can be combined and compared.
Dooley, Laurence S., Reel, Parminder Singh, Wong, Patrick   +2 more
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Reducing Uncertainty of Weak Supervised Signals via Mutual Information Techniques

IEEE Access
Weakly supervised learning (WSL) refers to training models using imperfect or noisy labels, which can significantly reduce the costs associated with manual labeling.
Yichen Liu, Hanlin Feng, Xin Zhang
doaj   +1 more source

Constellation Optimization in the Presence of Strong Phase Noise

, 2013
In this paper, we address the problem of optimizing signal constellations for strong phase noise. The problem is investigated by considering three optimization formulations, which provide an analytical framework for constellation design.
Amat, Alexandre Graell i, Colavolpe, Giulio, Eriksson, Thomas, Krishnan, Rajet   +3 more
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Decoding MRI-informed brain age using mutual information

Insights into Imaging
Objective We aimed to develop a standardized method to investigate the relationship between estimated brain age and regional morphometric features, meeting the criteria for simplicity, generalization, and intuitive interpretability.
Jing Li, Linda Chiu Wa Lam, Hanna Lu
doaj   +1 more source

Kolmogorov Capacity with Overlap

Entropy
The notion of δ-mutual information between non-stochastic uncertain variables is introduced as a generalization of Nair’s non-stochastic information functional.
Anshuka Rangi, Massimo Franceschetti
doaj   +1 more source