Results 51 to 60 of about 888,327 (305)

Fichte and Hegel on recognition and slavery [PDF]

open access: yes, 2016
In the first section of this essay I show how Hegel’s account of the struggle for recognition can be explained in terms of the role that Fichte accords to recognition in his deduction of the concept of right and, in particular, in terms of a problem to ...
409Merle   +69 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Practice and reflections on regional mutual recognition of clinical research ethics review——based on survey results from medical and health institutions in Jiangsu Province

open access: yesHolistic Integrative Oncology
With the continuous advancement of medical research, the number of multi-center clinical studies has been steadily increasing, bringing about significant challenges to ethical review.
Xiaolin Liu   +5 more
doaj   +1 more source

Those Who Shall Be Identified: The Data Protection Aspects of the Legal Framework for Electronic Identification in the European Union

open access: yesTalTech Journal of European Studies, 2021
The article focuses on the intersections of the regulation of electronic identification as provided in the eIDAS Regulation and data protection rules in the European Union.
Andraško Jozef, Mesarčík Matúš
doaj   +1 more source

Mutual recognition in goods and services: an economic perspective. Bruges European Economic Policy (BEEP) Briefing 2/2002 [PDF]

open access: yes, 2002
Mutual recognition is a remarkable innovation facilitating economic intercourse across borders. In the EU's internal goods market it has been helpful in tackling or avoiding the remaining obstacles, namely, regulatory barriers between Member States ...
Pelkmans, Jacques.
core  

A mutual information based adaptive windowing of informative EEG for emotion recognition [PDF]

open access: yes, 2018
Emotion recognition using brain wave signals involves using high dimensional electroencephalogram (EEG) data. In this paper, a window selection method based on mutual information is introduced to select an appropriate signal window to reduce the length ...
Piho, Laura, Tjahjadi, Tardi
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The Sky Is Not the Limit: Mutual Trust and Mutual Recognition après Aranyosi and Caldararu

open access: yesCroatian Yearbook of European Law and Policy, 2018
In the present article, judgments of the European Court of Justice, together with the case of Aranyosi and Căldăraru, are put under the academic microscope. The analysis is conducted through the lenses of domestic judges.
Adam Lazowski
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

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