Results 101 to 110 of about 67,846 (274)

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes   +7 more
wiley   +1 more source

The combination of macromastia and myasthenia. A case report

open access: yesЭндокринная хирургия, 2014
The article presents a rare clinical observation of combination of bilateral gigantomastia with myasthenia. The debut of myasthenia dangerous to sudden respiratory failure.
Valeriy Vital'evich Voskoboynikov   +4 more
doaj   +1 more source

Evaluation of the effectiveness and safety of anti‐CGRP monoclonal antibodies in patients with migraine and autoimmune diseases: IMMUNO‐CGRP study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to evaluate demographic characteristics, treatment effectiveness, and safety outcomes in patients with migraine undergoing anti‐calcitonin gene‐related peptide (CGRP) treatments regarding the presence of autoimmune diseases. Background CGRP has an important role in migraine pathophysiology through neuronal modulation
María Clara García‐Castillo   +37 more
wiley   +1 more source

Utility of the Predictive Summary Index for Comparison of Diagnostic Protocols in Myasthenia Gravis With Repetitive Nerve Stimulation and Concentric Needle Jitter

open access: yesBrain and Behavior
Introduction As sensitivity of a test can be increased at the expense of specificity, a quality measure taking into account both parameters is desirable.
Peter Trillenberg   +1 more
doaj   +1 more source

VIDEO-ASSISTED THORACOSCOPIC THYMECTOMY IN MYASTHENIA. A NEW APPROACH

open access: yesВестник анестезиологии и реаниматологии, 2018
The objective of the study: to perform clinical efficiency assessment of epidural anesthesia combined with an epiglottic airway and auxiliary pulmonary ventilation in video-assisted thoracoscopic thymectomies.Subjects and methods.
V. A. Zhikhаrev   +4 more
doaj   +1 more source

Randomized controlled trial of intravenous dexamethasone to prevent relapse in the treatment of migraine in a pediatric emergency department

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to evaluate whether a single dose of intravenous dexamethasone, when added to standard abortive therapy, reduces relapse of migraine after emergency department (ED) discharge in children and adolescents. Background Migraine is a leading cause of headache presentations to the ED for children and adolescents.
Geneviève Tourigny‐Ruel   +3 more
wiley   +1 more source

The Use of Parabulbar and Sub‐Tenon Injections to Correct Isolated Resistant Diplopia in Patients With Generalized Myasthenia Gravis: A Long Road to Clinically Meaningful Success

open access: yesClinical Case Reports
Parabulbar betamethasone provided rapid and durable relief of isolated, treatment‐resistant diplopia in seronegative myasthenia gravis after multiple systemic therapy failures, suggesting that targeted periocular corticosteroid delivery may be a steroid ...
M. Marchuk   +3 more
doaj   +1 more source

Barnes Hospital Bulletin [PDF]

open access: yes, 1981
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1188/thumbnail ...

core   +1 more source

Effects of Meal Consumption on Isotonic Lingual Endurance in Healthy Adults: A Multi‐Institutional Study

open access: yesJournal of Oral Rehabilitation, EarlyView.
Isotonic tongue endurance was measured pre‐ and post‐meal using the Iowa Oral Performance Instrument (IOPI) in healthy younger (18–35 years) and older (≥ 65 years) adults. Older adults demonstrated greater isotonic endurance and longer mealtimes, with no sex differences in endurance.
Yvette M. McCoy   +8 more
wiley   +1 more source

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