Results 81 to 90 of about 47,298 (270)
BMC MedicineBackground To identify the associations between thymic pathology and the prognosis of myasthenia gravis (MG) patients. Methods In this multicenter retrospective study, 1,254 myasthenia gravis (MG) patients who underwent thymectomy across four clinical ...
Moli Fan +11 more
doaj +1 more source
Indian Journal of Endocrinology and Metabolism, 2013 Thyroid associated orbitopathy, although seen most commonly with thyrotoxicosis, is also known to occur in primary hypothyroidism. Myasthenia gravis is an autoimmune condition with an established association with autoimmune thyroid disease. We report the
Chitra Selvan +11 more
doaj +1 more source
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims Degradation of cell‐surface acetylcholine receptors (AChRs) by antigenic modulation is a key pathogenic mechanism of myasthenia gravis (MG) autoantibodies, yet standard assays primarily detect antibody binding rather than functional effects.
Peng Du +7 more
wiley +1 more source
Muscle &Nerve, EarlyView.ABSTRACT Urinary dysfunction has been reported in association with myasthenic syndromes, including myasthenia gravis (MG), Lambert–Eaton myasthenic syndrome (LEMS), and congenital myasthenic syndromes (CMS), but evidence regarding its prevalence, clinical impact, pathophysiology, and management remains limited.
Julia M. Augustin +13 more
wiley +1 more source
Botulinum toxin use in patients with neurological disorders: A U.S.‐based claims database analysis
PM&R, EarlyView.Abstract Background and Objective Real‐world evidence describing long‐term persistency with botulinum toxin (BoNT) therapy is limited. We assessed treatment patterns and persistency with BoNT in clinical practice over 2 years. Design Retrospective, longitudinal, claims database analysis. Setting Medical claims data from the Merative MarketScan database
David M. Simpson +4 more
wiley +1 more source
Clinical and functional studies of autoimmune disorders of neuromuscular transmission
, 2015 Inherited and acquired disorders of the neuromuscular junction are an important cause of muscle weakness and fatigability. In this thesis I focus on the autoimmune disorders of neuromuscular transmission.
Spillane, J
core
Myasthenia Gravis – a new era of treatment options
Myasthenia Gravis is an autoimmune disease of the neuromuscular junction that causes fluctuating fatigable neuromuscular weakness. The spectrum of severity ranges from mild intermittent ptosis to respiratory failure requiring ventilatory support ...
Jennifer Spillane, Narmathey Thambirajah
core +2 more sources
Current and emerging treatments for the management of myasthenia gravis
, 2011 Sivakumar SathasivamThe Walton Centre NHS Foundation Trust, Lower Lane, Liverpool, UKAbstract: Myasthenia gravis is an autoimmune neuromuscular disorder.
Sathasivam S, Sivakumar Sathasivam
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Clinical Presentations of Myasthenia Gravis [PDF]
, 2018 This chapter describes signs and symptoms characteristic for postsynaptic neuromuscular junction diseases, how to validate them, and when to attribute them to myasthenia or another neurological disease.
Kuks, Jan B.M., Jan B. M. Kuks
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Veterinary Record, EarlyView.Abstract Background Non‐ambulatory tetraparesis or tetraplegia in cats may constitute a diagnostic challenge for general practitioners. Therefore, this study aimed to evaluate if clinical variables from signalment, history, clinical examination and basic ancillary tests are associated with underlying diagnoses in cats with non‐ambulatory tetraparesis ...
Guido Bertoldi, Steven De Decker
wiley +1 more source