Results 61 to 70 of about 52,376 (272)

Myasthenia gravis

The Lancet, 2001
Myasthenia gravis is an autoimmune disorder mainly caused by antibodies to the muscle acetylcholine receptors (AChRs) at the neuromuscular junction. Loss of these receptors leads to a defect in neuromuscular transmission with muscle weakness and fatigue.
Vincent, A, Palace, J, Hilton-Jones, D
openaire   +2 more sources

Interleukin‐2 Deprived State of Regulatory T cells and Their Recovery by Low‐Dose Interleukin‐2 in Patients With Inflammatory Myopathies

Arthritis &Rheumatology, EarlyView.
Objective Regeneration and expansion of Treg by low‐dose interleukin‐2 (IL‐2) therapy is considered a potential treatment strategy for a wide range of autoimmune diseases. To provide a pathophysiologically‐based rationale for low‐dose IL‐2 therapy, we investigated whether reversible defects in the Treg–IL‐2 axis emerge in inflammatory myopathies ...
Justus Ohmes, Luisa R. Monne, Sara Comdühr, Fynn Gerlach, Hanna Grasshoff, Alexander Dübbers, Antje Müller, Alexander Scheffold, Gabriela Riemekasten, Reza Akbarzadeh, Jens Y. Humrich   +10 more
wiley   +1 more source

Tyrosine phosphatase SHP2 accelerated progression of thymic epithelial tumors via promoting PI3K/ERK/CREB/SP1 induced HIF1α and EGFR expression

European Journal of Medical Research
Objective To investigate the impact of SHP2 on thymic epithelial tumors (TETs) and its underlying mechanisms. Methods Bioinformatic analysis was performed to identify key pathways in TETs.
Congya Yan, Shuai Zhao, Guoyan Qi
doaj   +1 more source

Anti-MuSK antibody positive myasthenia gravis with childhood onset [PDF]

Romanian Journal of Neurology, 2016
Myasthenic syndromes are acquired diseases which unite the impairment of neuromuscular transmission with associated muscle weakness, occasional positive anti-acetylcholine or MuSK antibodies and characteristic electrodiagnostic features.
Diana Epure, Smaranda Nita, Raluca Ioana Teleanu   +2 more
doaj   +1 more source

Anaesthetic Management of Myasthenia Gravis with Thymic Mass in Facial Trauma [PDF]

, 2010
Myasthenia gravis is an immunologic disorder characterised by polyclonal antibodies directed against nicotinic acetylcholine receptors at postneuromuscular junction.
Dheer Singh, Deepak Sharma
core  

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

SCANNING ELECTRON MICROSCOPY OF “ROSA” FILTER ELEMENTS FROM HEMOFENIX APPARATUS, AND OF BLOOD IN MEMBRANE PLASMAPHERESIS AND LASER IRRADIATION

Вестник трансплантологии и искусственных органов, 2013
Aim. To study with scanning electron microscopy an interaction between structural elements of “Rosa” filters (a component of HEMOFENIХ) with erythrocytes during membrane plasmapheresis and under the effect of la- ser irradiation performed during ...
I. M. Baybekov, A. K. Butaev, B. A. Saidkhanov   +2 more
doaj   +1 more source

Treatment‐Related Adverse Events and Health‐Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell, E. C. Ward, L. R. Wishart, R. Perera, C. Barrett, K. A. Edmiston, E. Mitchell, A. Pigott, R. Pitt, K. Russell, B. A. Chan, R. Ladwa   +11 more
wiley   +1 more source

Serum fibrinogen is not elevated in patients with myasthenia gravis

Scientific Reports
Myasthenia gravis (MG) is an autoimmune, autoantibody-mediated disease characterized by fatigable weakness of skeletal muscles. MG is a heterogeneous disease that currently lacks a robust biomarker for diagnosing all subtypes.
Taylor A. Bauman, Sean M. Lee, Vern C. Juel, Yingkai Li, Karli Gilbert, Jiaxin Chen, Henry J. Kaminski, Linda L. Kusner, MGNet Investigators   +8 more
doaj   +1 more source

Ocular Myasthenia

Diplopia and ptosis are among the most common symptoms of myasthenia gravis, with a variety of physiological reasons underpinning the susceptibility of the extraocular muscles.
Benatar, Michael, Wong, Sui Hsien
core   +1 more source