Results 71 to 80 of about 52,376 (272)

Early onset bilateral juvenile myasthenia gravis masquerading as simple congenital ptosis

, 2017
Myasthenia gravis is an autoimmune disorder affecting the neuromuscular junction. Ocular myasthenia gravis presents as ptosis with extraocular motility restriction and is prone to be misdiagnosed as third nerve palsy or congenital or aponeurotic ptosis ...
Alam, MS, Devi Nivean, P, Devi Nivean, Pratheeba, Alam, Md. Shahid   +3 more
core   +1 more source

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Sublingual Zolpidem for MRI in Claustrophobic Patients: A Prospective, Non‐Randomized Noninferiority Study

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Claustrophobia during MRI may lead to examination interruption, motion artifacts, prolonged acquisition time, and reduced diagnostic quality, frequently requiring intravenous sedation to ensure successful examination completion and adequate image acquisition.
Beatriz Birelli do Nascimento, Fernando de Sá Del Fiol, Marcus Vinicius Birelli do Nascimento, Lucas Bueno de Oliveira, Samanta Aparecida Alves, Lucas do Nascimento Bernardes   +5 more
wiley   +1 more source

Miastenia gravis: perfil clínico de uma série de 20 casos. [PDF]

, 2008
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Braga, Fernando Martins
core  

Bilateral Ophthalmoplegia After Neoadjuvant Pembrolizumab for Oral Cavity Squamous Cell Carcinoma

The Laryngoscope, EarlyView.
The role of immune checkpoint inhibition (ICI) therapy in the treatment of head and neck squamous cell carcinoma (HNSCC) is expanding with increased utilization of neoadjuvant and adjuvant pembrolizumab in the setting of locally advanced disease. This report describes the presentation and management of the first known case of pembrolizumab‐induced ...
Leonard E. Estephan, Peter Jacoby, David M. Cognetti, Steven A. Manobianco   +3 more
wiley   +1 more source

Remission of Myasthenia Gravis: Clinical, Electrophysiological and Immunological Studies [PDF]

, 1993
1993-03The prognosis of 142 patients with myasthenia gravis (MG) was clinically investigated. Forty-nine (35%) had clinical remission (CR) and 23 (16%) good improvement (GI), while 70 (49%) remained in poor condition.
TAKEGAMI, TOSHIHIKO, MANO, KAZUO, TAKAHASHI, AKlRA, OKAMOTO, SUSUMU   +3 more
core   +1 more source

Fatigue in Myasthenia Gravis: Recent Advances and Emerging Concepts

Muscle &Nerve, EarlyView.
ABSTRACT Fatigue is a common, often disabling symptom in myasthenia gravis (MG), distinct from muscle fatigability, and strongly associated with reduced quality of life. This narrative review examines current evidence on fatigue in MG, its patient impact, and future research directions. Earlier studies, mostly small and heterogeneous, reported a highly
Yvonne J. M. Campman, Martijn R. Tannemaat, Annabel M. Ruiter, Sarah Hoffmann   +3 more
wiley   +1 more source

Proteomic and machine learning analysis predicts treatment response signatures in Myasthenia Gravis

Journal of Translational Medicine
Background Myasthenia gravis (MG) is a prototypical antibody-mediated autoimmune disease with variable treatment responses with a need for biomarkers to guide therapeutic decision making.
Karli Gilbert, Amrita K. Cheema, Henry J. Kaminski, Linda L. Kusner   +3 more
doaj   +1 more source

Presynaptic Congenital Myasthenic Syndromes

Muscle &Nerve, EarlyView.
ABSTRACT Presynaptic congenital myasthenic syndromes (CMS) encompass a large number of rare neurologic disorders caused by impaired release of acetylcholine (ACh) from motor nerve terminals. There are two main groups of presynaptic CMS: one in which the amount of ACh in synaptic vesicles (SV) is diminished and another in which the mechanism of synaptic
Ricardo A. Maselli
wiley   +1 more source

Refractory myasthenia gravis – clinical profile, comorbidities and response to rituximab

, 2016
Introduction: Myasthenia gravis (MG) is an antibody mediated autoimmune neuromuscular disorder characterized by fatigable muscle weakness. A proportion of myasthenia gravis patients are classified as refractory due to non responsiveness to conventional ...
Gummadi, S, Burra, HK, Sodalagunta, MB, Settikere Nataraju, Aravinda, Gummadi, Siddharth, Sudulagunta, SR, Burra, Hemanth Kumar, Sepehrar, M, Sathyanarayana, Deepak, Sudulagunta, Sreenivasa Rao, Bangalore Raja, Shiva Kumar, Sepehrar, Mona, Sodalagunta, Mahesh Babu, Settikere Nataraju, A, Sathyanarayana, D, Bangalore Raja, SK   +15 more
core   +1 more source