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Of Mice and Myc: c-Myc and Mammary Tumorigenesis
Journal of Mammary Gland Biology and Neoplasia, 2004The proto-oncogene c- myc is involved in regulating proliferation and apoptosis, and its deregulation via genomic and postgenomic mechanisms, contributes to the development and progression of multiple human cancers, including those of the breast.
M Hunter, Jamerson +2 more
openaire +2 more sources
2006
Myc regulates to some degree every major process in the cell. Proliferation, growth, differentiation, apoptosis, and metabolism are all under myc control. In turn, these processes feed back to adjust the level of c-myc expression. Although Myc is regulated at every level from RNA synthesis to protein degradation, c-myc transcription is particularly ...
J, Liu, D, Levens
openaire +2 more sources
Myc regulates to some degree every major process in the cell. Proliferation, growth, differentiation, apoptosis, and metabolism are all under myc control. In turn, these processes feed back to adjust the level of c-myc expression. Although Myc is regulated at every level from RNA synthesis to protein degradation, c-myc transcription is particularly ...
J, Liu, D, Levens
openaire +2 more sources
The MYC oncogene — the grand orchestrator of cancer growth and immune evasion
Nature Reviews Clinical Oncology, 2021Renumathy Dhanasekaran +2 more
exaly
Direct Phosphorylation and Stabilization of MYC by Aurora B Kinase Promote T-cell Leukemogenesis
Cancer Cell, 2020Jue Jiang, Xiaolian Cai, Chao Wu
exaly
Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy
Cancer Cell, 2019Huiying Han +2 more
exaly