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Circulating Beta3-Adrenoreceptor as Novel Independent Biomarker for Risk Assessment in Neuroblastoma Patients. [PDF]
Favre C +20 more
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Alternative Splicing of the NF-Y Subunit, NF-YA, in Neuroblastoma Phenotype Heterogeneity. [PDF]
Martelli I +4 more
europepmc +1 more source
A taurine metabolism-related gene program defines clinical and biological features of neuroblastoma and yields an 8-gene candidate prognostic model. [PDF]
Zhong B +5 more
europepmc +1 more source
The MYCN Protein in Health and Disease [PDF]
MYCN is a member of the MYC family of proto-oncogenes. It encodes a transcription factor, MYCN, involved in the control of fundamental processes during embryonal development. The MYCN protein is situated downstream of several signaling pathways promoting cell growth, proliferation and metabolism of progenitor cells in different developing organs and ...
Marie Arsenian Henriksson +1 more
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MYCN gain and MYCN amplification in a stage 4S neuroblastoma
Cancer Genetics and Cytogenetics, 2003Stage 4S neuroblastoma is a disease associated with spontaneous regression and good survival. We present a patient whose evolution has shown the variety and complexity of this disease in infants. Biologic factors, such as ploidy, MYCN copy number, loss of 1p36, and other chromosomal gains and losses were determined.
Rosa, Noguera +7 more
openaire +2 more sources
Cancer Letters, 2004
MYCN is a member of the MYC family of oncogenes that encode nuclear proteins serving as transcription factors. Activation of MYC family genes, usually by genetic damage with the consequence of enhanced expression of a wild-type protein, has been found to participate in human and animal cancers.
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MYCN is a member of the MYC family of oncogenes that encode nuclear proteins serving as transcription factors. Activation of MYC family genes, usually by genetic damage with the consequence of enhanced expression of a wild-type protein, has been found to participate in human and animal cancers.
openaire +2 more sources
2015
MicroRNAs (miRNAs) are small noncoding RNAs that downregulate translation of mRNAs into proteins by specifically binding the 3′-untranslated regions (UTRs).
Althoff, Kristina, Schulte, Johannes
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MicroRNAs (miRNAs) are small noncoding RNAs that downregulate translation of mRNAs into proteins by specifically binding the 3′-untranslated regions (UTRs).
Althoff, Kristina, Schulte, Johannes
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MYCN Amplification by Differential PCR
Pediatric Hematology and Oncology, 1993A method is described to estimate MYCN (N-myc) oncogene amplification in neuroblastoma by the technique of differential polymerase chain reaction (PCR). The technique is quicker than conventional Southern blotting techniques and does not require radioactive materials.
S N, Huddart +3 more
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MYCN immunohistochemistry as surrogate marker for MYCN-amplified spinal ependymomas
Human CellMYCN (master regulator of cell cycle entry and proliferative metabolism) gene amplification defines a molecular subgroup of spinal cord ependymomas that show high-grade morphology and aggressive behavior. Demonstration of MYCN amplification by DNA methylation or fluorescence-in situ hybridization (FISH) is required for diagnosis. We aimed to (i) assess
Divya, Mohan +10 more
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