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Identification of Mycobacteria

Military Medicine, 1967
Summary An identification system for the genus Mycobacterium is presented, based on data from 637 strains. The identification process consists of two steps: the first, preliminary grouping, by which test strains are grouped into either the subgenus Mycobacterium (slowly growing mycobacteria) or the subgenus Mycomycobacterium (rapidly growing ...
John N. Albertson, Joseph R. Creitz
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Electroporation of Mycobacteria

2003
High-efficiency transformation is a major limitation in the study of mycobacteria. The genus Mycobacterium can be difficult to transform; this is mainly caused by the thick and waxy cell wall but is compounded by the fact that most molecular techniques have been developed for distantly related species such as Escherichia coli and Bacillus subtilis.
Tanya Parish, Neil G. Stoker
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Electroporation of Mycobacteria

2015
High-efficiency transformation of DNA is integral to the study of mycobacteria, allowing genetic manipulation. Electroporation is the most widely used method for introducing DNA into mycobacterial strains. Many parameters contribute to high-efficiency transformation; these include the species per strain, the transforming DNA, the selectable marker, the
Goude, Renan   +2 more
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Nontuberculous Mycobacteria

Seminars in Respiratory and Critical Care Medicine, 2021
AbstractNontuberculous mycobacteria (NTM) are ubiquitous in the environment and 193 species of NTM have been discovered thus far. NTM species vary in virulence from benign environmental organisms to difficult-to-treat human pathogens. Pulmonary infections remain the most common manifestation of NTM disease in humans and bronchiectasis continues to be a
Shera, Tan, Shannon, Kasperbauer
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Nontuberculous mycobacteria

2008
This chapter focuses on nontuberculous mycobacteria (NTM), organisms that are ubiquitous in the environment and are thus referred as “environmental mycobacteria” by some experts. Mycobacterium avium complex (MAC), which includes M. kansasii, M. fortuitum, and M. abscessus, is the most common NTM associated with human disease in the United States.
David E. Griffith, Timothy R. Aksamit
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Immunotherapy with mycobacteria

Current Opinion in Allergy and Clinical Immunology, 2003
To summarize and evaluate critically recent progress with mycobacteria as a potential novel disease modifying treatment strategy in asthma.The link between exposure to pathogenic or saprophytic mycobacteria and protection from allergic diseases is still controversial, and recent epidemiological studies, which addressed only exposure to Mycobacterium ...
Christoph Walker   +2 more
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Culturing Mycobacteria

2021
Building upon the foundational research of Robert Koch, who demonstrated the ability to grow Mycobacterium tuberculosis for the first time in 1882 using media made of coagulated bovine serum, microbiologists have continued to develop new and more efficient ways to grow mycobacteria.
Elizabeth, Wallace   +19 more
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Mycobacteria and autoimmunity

Lupus, 2015
Mycobacterial infections can cause a variety of different manifestations. The increasing incidence of these infections worldwide brought another medical dilemma: immunological manifestations characterized by the presence of many autoantibodies and concomitant presence of autoimmune diseases.
F Machado Ribeiro, T Goldenberg
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Pathogenomics of Mycobacteria

2009
Among the 130 species that constitute the genus Mycobacterium, the great majority are harmless saprophytes. However, a few species have very efficiently adapted to a pathogenic lifestyle. Among them are two of the most important human pathogens, Mycobacterium tuberculosis and Mycobacterium leprae, and one emerging pathogen, Mycobacterium ulcerans ...
Roland Brosch   +2 more
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Mycobacteria: An Overview

Clinical Infectious Diseases, 1981
This International Conference on Atypical Mycobacteria, a gathering of outstanding scientists of many fields, attests to the biologic and clinical importance of the mycobacteria and mycobacterioses. This conference may help provide a basis for the formulation of cooperative projects for the attainment of knowledge in each of several fields where I ...
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