Results 181 to 190 of about 367,380 (311)

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

<i>Mycobacterium fortuitum</i>: Diagnostic and treatment challenges of skin disease in an immunocompetent host. [PDF]

IDCases
Conradie M, Egan C, O'Regan S, Conlon P, Reidy P, Gallagher D, Higgins E.   +6 more
europepmc   +1 more source

Catalysis and allostery in bacterial ATP phosphoribosyltransferases

The FEBS Journal, EarlyView.
ATP phosphoribosyltransferase (ATPPRT) catalyses the first reaction of L‐histidine biosynthesis. L‐Histidine allosterically inhibits ATPPRT to regulate this energy‐intensive pathway in histidine‐synthesising organisms, such as bacteria, archaea and plants.
Lillian G. Bates, Rafael G. da Silva
wiley   +1 more source

Clinical utility of whole-genome sequencing in identifying a rare <i>Mycobacterium</i> species causing native joint infection. [PDF]

ASM Case Rep
Globan M, Moselen J, Wang N, Steinig E, Nong Y, Viberg L, Caly L, Bond KA.   +7 more
europepmc   +1 more source

Single‐centre analysis of severe Coombs‐positive autoimmune haemolytic anaemia in an HIV‐endemic population

HIV Medicine, EarlyView.
Abstract Introduction Human immunodeficiency virus (HIV) is a rare cause of autoimmune haemolytic anaemia (AIHA) which requires prompt diagnosis and treatment. We compared clinical and laboratory findings in AIHA patients with and without HIV. Methods We included adults with severe AIHA (haemoglobin ≤8 g/dL) diagnosed at a tertiary academic centre ...
Kathleen O. De John, Karryn Brown, Jenna Bailey, Estelle R. Verburgh, Jessica J. Opie   +4 more
wiley   +1 more source

<i>Mycobacterium mageritense</i> submandibular lymphadenitis in children: diagnostic challenges and the role of metagenomic next-generation sequencing: two case reports and literature review. [PDF]

Front Med (Lausanne)
Li L, Xing Z, Liu L, Mu X, Zhai Y, Luan S, Li J, Guo Q.   +7 more
europepmc   +1 more source

Can Artificial Intelligence Be Utilised to Develop Point‐of‐Care Endodontic Microbiological Technologies?

International Endodontic Journal, EarlyView.
ABSTRACT Background Primary or persistent endodontic disease is caused by microbial biofilms that irritate the pulp and periapical tissues. Extensive microbiological analyses of these biofilms and their constituent pathogens have revealed their diversity and complexity.
Ashraf F. Fouad
wiley   +1 more source

Corrigendum to TREM-2 promotes Th1 responses by interacting with the CD3ζ-ZAP70 complex following Mycobacterium tuberculosis infection. [PDF]

J Clin Invest
Wu Y, Wu M, Ming S, Zhan X, Hu S, Li X, Yin H, Cao C, Liu J, Li J, Wu Z, Zhou J, Liu L, Gong S, He D, Huang X.   +15 more
europepmc   +1 more source

Defensins and Regulated Cell Death Effectors: Convergent Mechanisms of Membrane Targeting in Innate Immunity

Immunology &Cell Biology, EarlyView.
Defensins, gasdermins and MLKL are distinct innate immune effectors with membrane disrupting activities that span antimicrobial defence and inflammatory cell death. This review compares the structure and function of these key molecules across four connected processes of (1) protein expression and activation, (2) lipid specific recognition and ...
Serenay B. Demir, Gavan J. Francis, Nicholas Bronchinetti, Mark D. Hulett   +3 more
wiley   +1 more source

Pulmonary disease caused by <i>Mycobacterium meguroense</i>, a newly identified slow-growing mycobacterium, after umbilical cord blood transplantation: A case report from Japan and a mini-review of the literature. [PDF]

New Microbes New Infect
Iizuka S, Yoshida M, Shinozaki T, Uwamino Y, Inose R, Oyamada Y, Fukunaga K, Asakura T, Namkoong H.   +8 more
europepmc   +1 more source