Tuberculous meningitis (TBM) is the most devastating form of extrapulmonary Mycobacterium tuberculosis infection in humans. Severe inflammation and extensive tissue damage drive the morbidity and mortality of this manifestation of tuberculosis (TB ...
Ranjeet Kumar +5 more
doaj +1 more source
Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum [PDF]
As nonreplicating tubercle bacilli are tolerant to the cidal action of antibiotics and resistant to multiple stresses, identification of this persister-like population of tubercle bacilli in sputum presents exciting and tractable new opportunities to ...
Alvarez +77 more
core +4 more sources
Spatiotemporal co-existence of two Mycobacterium ulcerans clonal complexes in the Offin River Valley of Ghana [PDF]
In recent years, comparative genome sequence analysis of African Mycobacterium ulcerans strains isolated from Buruli ulcer (BU) lesion specimen has revealed a very limited genetic diversity of closely related isolates and a striking association between ...
Aboagye, Samuel +11 more
core +2 more sources
Macrophages being the connecting link between innate and adaptive immune system plays a crucial role in microbial antigen presentation and orchestrates the subsequent clearance of microorganisms.
Saradindu Saha +2 more
doaj +1 more source
An immunocompromised dialysis patient with skin and bone lesions [PDF]
Patients with chronic kidney failure have disturbances of immune function involving both innate and adaptive systems. These result in both immunodepression which increases susceptibility to infection and immunoactivation leading to a chronic inflammatory
Brown +7 more
core +2 more sources
A robust SNP barcode for typing Mycobacterium tuberculosis complex strains [PDF]
Strain-specific genomic diversity in the Mycobacterium tuberculosis complex (MTBC) is an important factor in pathogenesis that may affect virulence, transmissibility, host response and emergence of drug resistance.
A McKenna +33 more
core +2 more sources
Peptidomic analysis of mycobacterial secreted proteins enables species identification
Pulmonary disease arising from slow‐growing mycobacterial infections has emerged as an increasingly prevalent clinical concern over the past two to three decades.
Qingbo Shu +10 more
doaj +1 more source
Tuberculosis primaria de esófago: reporte de caso
Mujer de 60 años, natural de Tarma y procedente de Lima, con antecedentes de exposición a biomasas, contacto con paciente con tuberculosis, hipertensión arterial, arritmia cardiaca, y madre con cáncer de ovario. La paciente acude a consulta con un cuadro
Karina Ivonne Orihuela Lazo +3 more
doaj +1 more source
Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam +3 more
core +3 more sources
Protection efficacy of Argentinian isolates of Mycobacterium avium subsp. paratuberculosis with different genotypes and virulence in a murine model [PDF]
Paratuberculosis is a chronic disease caused by Mycobacterium avium subsp. paratuberculosis (Map). The disease causes economic losses and, therefore, it is imperative to follow proper control strategies, which should include an effective vaccine. Several
Alvarado Pinedo, María Fiorella +8 more
core +1 more source

