Results 21 to 30 of about 530,034 (290)

Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Tuberculous meningitis (TBM) is the most devastating form of extrapulmonary Mycobacterium tuberculosis infection in humans. Severe inflammation and extensive tissue damage drive the morbidity and mortality of this manifestation of tuberculosis (TB ...
Ranjeet Kumar   +5 more
doaj   +1 more source

Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum [PDF]

open access: yes, 2008
As nonreplicating tubercle bacilli are tolerant to the cidal action of antibiotics and resistant to multiple stresses, identification of this persister-like population of tubercle bacilli in sputum presents exciting and tractable new opportunities to ...
Alvarez   +77 more
core   +4 more sources

Spatiotemporal co-existence of two Mycobacterium ulcerans clonal complexes in the Offin River Valley of Ghana [PDF]

open access: yes, 2016
In recent years, comparative genome sequence analysis of African Mycobacterium ulcerans strains isolated from Buruli ulcer (BU) lesion specimen has revealed a very limited genetic diversity of closely related isolates and a striking association between ...
Aboagye, Samuel   +11 more
core   +2 more sources

“It Takes Two to Tango”: Role of Neglected Macrophage Manipulators Coronin 1 and Protein Kinase G in Mycobacterial Pathogenesis

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Macrophages being the connecting link between innate and adaptive immune system plays a crucial role in microbial antigen presentation and orchestrates the subsequent clearance of microorganisms.
Saradindu Saha   +2 more
doaj   +1 more source

An immunocompromised dialysis patient with skin and bone lesions [PDF]

open access: yes, 2010
Patients with chronic kidney failure have disturbances of immune function involving both innate and adaptive systems. These result in both immunodepression which increases susceptibility to infection and immunoactivation leading to a chronic inflammatory
Brown   +7 more
core   +2 more sources

A robust SNP barcode for typing Mycobacterium tuberculosis complex strains [PDF]

open access: yes, 2014
Strain-specific genomic diversity in the Mycobacterium tuberculosis complex (MTBC) is an important factor in pathogenesis that may affect virulence, transmissibility, host response and emergence of drug resistance.
A McKenna   +33 more
core   +2 more sources

Peptidomic analysis of mycobacterial secreted proteins enables species identification

open access: yesView, 2022
Pulmonary disease arising from slow‐growing mycobacterial infections has emerged as an increasingly prevalent clinical concern over the past two to three decades.
Qingbo Shu   +10 more
doaj   +1 more source

Tuberculosis primaria de esófago: reporte de caso

open access: yesHorizonte Médico, 2021
Mujer de 60 años, natural de Tarma y procedente de Lima, con antecedentes de exposición a biomasas, contacto con paciente con tuberculosis, hipertensión arterial, arritmia cardiaca, y madre con cáncer de ovario. La paciente acude a consulta con un cuadro
Karina Ivonne Orihuela Lazo   +3 more
doaj   +1 more source

Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]

open access: yes, 2015
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam   +3 more
core   +3 more sources

Protection efficacy of Argentinian isolates of Mycobacterium avium subsp. paratuberculosis with different genotypes and virulence in a murine model [PDF]

open access: yes, 2018
Paratuberculosis is a chronic disease caused by Mycobacterium avium subsp. paratuberculosis (Map). The disease causes economic losses and, therefore, it is imperative to follow proper control strategies, which should include an effective vaccine. Several
Alvarado Pinedo, María Fiorella   +8 more
core   +1 more source

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