Results 31 to 40 of about 333,477 (312)

Something Old, Something New: Ion Channel Blockers as Potential Anti-Tuberculosis Agents

Frontiers in Immunology, 2021
Tuberculosis (TB) remains a challenging global health concern and claims more than a million lives every year. We lack an effective vaccine and understanding of what constitutes protective immunity against TB to inform rational vaccine design.
Steven C. Mitini-Nkhoma, Elizabeth T. Chimbayo, David T. Mzinza, David T. Mzinza, David V. Mhango, David V. Mhango, Aaron P. Chirambo, Christine Mandalasi, Agness E. Lakudzala, Dumizulu L. Tembo, Kondwani C. Jambo, Kondwani C. Jambo, Henry C. Mwandumba, Henry C. Mwandumba   +13 more
doaj   +1 more source

Mycobacterium tuberculosis Beijing genotype. [PDF]

, 2003
Molecular epidemiologic studies of strains of Mycobacterium tuberculosis are currently conducted worldwide. The genetically distinct Beijing family of strains has been associated with large outbreaks of tuberculosis, increased virulence, and multidrug ...
Lillebaek, Troels, Judith R. Glynn, Andersen, Åse B., Troels Lillebaek, Glynn, Judith R., Kremer, Kristin, Åse B. Andersen, Asger Dirksen, Kristin Kremer, Andersen, Ase B, Glynn, Judith R, Dirksen, Asger   +11 more
core   +1 more source

Mycolicibacterium smegmatis, Basonym Mycobacterium smegmatis, Expresses Morphological Phenotypes Much More Similar to Escherichia coli Than Mycobacterium tuberculosis in Quantitative Structome Analysis and CryoTEM Examination

Frontiers in Microbiology, 2018
A series of structome analyses, that is, quantitative and three-dimensional structural analysis of a whole cell at the electron microscopic level, have already been achieved individually in Exophiala dermatitidis, Saccharomyces cerevisiae, Mycobacterium ...
Hiroyuki Yamada, Masashi Yamaguchi, Yuriko Igarashi, Kinuyo Chikamatsu, Akio Aono, Yoshiro Murase, Yuta Morishige, Akiko Takaki, Hiroji Chibana, Satoshi Mitarai, Satoshi Mitarai   +10 more
doaj   +1 more source

Molecular epidemiology of Mycobacterium africanum in Ghana [PDF]

, 2016
BACKGROUND: Mycobacterium africanum comprises two phylogenetic lineages within the M. tuberculosis complex (MTBC) and is an important cause of human tuberculosis (TB) in West Africa. The reasons for this geographic restriction of M.
Forson, Audrey, Yeboah-Manu, Dorothy, Esther Sarpong, Otchere, Isaac Darko, Borrell, Sonia, Clement Laryea, Gagneux, Sebastien, Frank Bonsu, Osei-Wusu, Stephen, Akosua Baddoo, Stephen Osei-Wusu, Ahorlu, Collins, Kwadwo A. Koram, Sarpong, Esther, Adwoa Asante-Poku, Collins Ahorlu, Audrey Forson, Laryea, Clement, Isaac Darko Otchere, Sebastien Gagneux, Bonsu, Frank, Hattendorf, Jan, Dorothy Yeboah-Manu, Sonia Borrell, Asante-Poku, Adwoa, Koram, Kwadwo A., Baddoo, Akosua, Jan Hattendorf   +27 more
core   +1 more source

Mycobacterium abscessus

Trends in Microbiology, 2021
No abstract ...
Boudehen, Yves-Marie, Kremer, Laurent
openaire   +3 more sources

Lack of immune responses to Mycobacterium tuberculosis DosR regulon proteins following Mycobacterium bovis BCG vaccination. [PDF]

, 2007
Mycobacterium bovis BCG is widely used as a vaccine against tuberculosis (TB), despite its variable protective efficacy. Relatively little is known about the immune response profiles following BCG vaccination in relation to protection against TB. Here we
Klein, Michèl R, Friggen, Annemieke H, Geluk, Annemieke, Lin, May Young, Verduyn, Marleen JC, Voskuil, Martin I, Huygen, Kris, Franken, Kees LMC, Smith, Steven G, van Meijgaarden, Krista E, Dockrell, Hazel M, Stewart, Amanda L, Ottenhoff, Tom HM   +12 more
core   +1 more source

A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. [PDF]

, 2007
The Mycobacterium tuberculosis TetR-type regulator Rv3574 has been implicated in pathogenesis as it is induced in vivo, and genome-wide essentiality studies show it is required for infection.
Withers, Mike, Moreland, NJ, Sidders, B, Ben Sidders, Catherine N. Soffair, Besra, Gurdyal; id_orcid, ten Bokum, A, Ten Bokum, A M C, Kendall, Sharon L, Soffair, CN, Sudagar Gurcha, Stoker, NG, Rosangela Frita, Gurdyal S. Besra, Besra, G S, Moreland, Nicole J, Moreland, N J, Kendall, SL, J. Shaun Lott, Sidders, Ben, Frita, R, Soffair, Catherine N, Neil G. Stoker, Frita, Rosangela, Soffair, C N, Mike Withers, Gurcha, S, Stoker, N G, Nicole J. Moreland, Auckland, Sydney, Birmingham, Gurcha, Sudagar, Sharon L. Kendall, Lott, J Shaun, Kendall, S L, Stoker, Neil G, Lott, J S, Ten Bokum, Annemieke, Withers, M, Lott, JS, Annemieke Ten Bokum, Besra, Gurdyal S   +41 more
core   +1 more source

Colorimetric phage-based assay for detection of rifampin-resistant Mycobacterium tuberculosis [PDF]

, 2007
Tests based on bacteriophage replication enable rapid screening of Mycobacterium tuberculosis for drug resistance. We describe a novel broth-based colorimetric method for detecting phage replication.
McNerney, R, Lemma, E, Urassa, Honorathy MR, Mallard, Kim, Lemma, Eshetu, Mallard, K, McNerney, Ruth, Urassa, HMR, Donoghue, HD, Donoghue, Helen D   +9 more
core   +1 more source

“It Takes Two to Tango”: Role of Neglected Macrophage Manipulators Coronin 1 and Protein Kinase G in Mycobacterial Pathogenesis

Frontiers in Cellular and Infection Microbiology, 2020
Macrophages being the connecting link between innate and adaptive immune system plays a crucial role in microbial antigen presentation and orchestrates the subsequent clearance of microorganisms.
Saradindu Saha, Payel Das, Somdeb BoseDasgupta   +2 more
doaj   +1 more source

Mycobacterium africanum is associated with patient ethnicity in Ghana [PDF]

, 2014
Mycobacterium africanum is a member of the Mycobacterium tuberculosis complex (MTBC) and an important cause of human tuberculosis in West Africa that is rarely observed elsewhere.
Yeboah-Manu, Dorothy, David Stucki, Otchere, Isaac Darko, Feldmann, Julia, Borrell, Sonia, Dorothy Yeboah-Manu (120059), Gagneux, Sebastien, Jan Hattendorf (113923), Emelia Danso, Adwoa Asante-Poku (335717), Samuel Y. Aboagye, Julia Feldmann (149820), Aboagye, Samuel Y., Stucki, David, Adwoa Asante-Poku, Sebastien Gagneux (149824), Isaac Darko Otchere, Sebastien Gagneux, Sonia Borrell (149821), Isaac Darko Otchere (682528), Julia Feldmann, Emelia Danso (120054), Hattendorf, Jan, Dorothy Yeboah-Manu, Sonia Borrell, David Stucki (149811), Asante-Poku, Adwoa, Samuel Y. Aboagye (567712), Danso, Emelia, Samuel Y Aboagye, Jan Hattendorf   +30 more
core   +1 more source