The genus Mycobacterium contains 188 species including several major human pathogens as well as numerous other environmental species. We report here comprehensive phylogenomics and comparative genomic analyses on 150 genomes of Mycobacterium species to ...
Radhey S. Gupta, Brian Lo, Jeen Son
semanticscholar +1 more source
Nontuberculosis mycobacterial (NTM) infections are increasing in prevalence across the world. In many cases, treatment options for these infections are limited. However, there has been progress in recent years in the development of new antimycobacterial drugs.
Sacha J. Pidot+3 more
openaire +6 more sources
“Mycobacterium indicus pranii” Is a Strain of Mycobacterium intracellulare [PDF]
In the recent publication “Comparative Analyses of Nonpathogenic, Opportunistic, and Totally Pathogenic Mycobacteria Reveal Genomic and Biochemical Variabilities and Highlight the Survival Attributes of Mycobacterium tuberculosis,” Rahman et al.
Christine Turenne+2 more
openaire +4 more sources
An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection
Tuberculosis, a major health problem in developing countries, has reemerged in recent years in many industrialized countries. The increased susceptibility of immunocompromised individuals to tuberculosis, and many experimental studies indicate that T ...
J. Flynn+5 more
semanticscholar +1 more source
Mycobacterium tuberculosis lineage: a naming of the parts [PDF]
There have been many reports of groups of related Mycobacterium tuberculosis strains described variously as lineages, families or clades. There is no objective definition of these groupings making it impossible to define relationships between those ...
Bellamy+25 more
core +1 more source
Additional Serotypes of Mycobacterium scrofulaceum, Mycobacterium gordonae, Mycobacterium marinum, and Mycobacterium xenopi Determined by Agglutination [PDF]
Agglutination serotypes were investigated by testing mycobacterial cultures from various sources with a large battery of antisera raised in rabbits. Absorption of agglutinins was performed when necessary to clarify serological relationships. Types in addition to those already described were recognized as follows: Mycobacterium scrofulaceum, serotype ...
Emanuel Wolinsky+2 more
openaire +2 more sources
A robust SNP barcode for typing Mycobacterium tuberculosis complex strains [PDF]
Strain-specific genomic diversity in the Mycobacterium tuberculosis complex (MTBC) is an important factor in pathogenesis that may affect virulence, transmissibility, host response and emergence of drug resistance.
A McKenna+33 more
core +2 more sources
Isolation, identification, and structural analysis of the mycobactins of Mycobacterium avium, Mycobacterium intracellulare, Mycobacterium scrofulaceum, and Mycobacterium paratuberculosis [PDF]
Methods were devised to purify the cell-associated, iron-binding compounds known as mycobactins from the closely related species Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum (i.e., the MAIS complex of organisms). The mycobactins from these three species showed a structure that is common to the mycobactins from all ...
R Barclay, Colin Ratledge, D F Ewing
openaire +3 more sources
Spatiotemporal co-existence of two Mycobacterium ulcerans clonal complexes in the Offin River Valley of Ghana [PDF]
In recent years, comparative genome sequence analysis of African Mycobacterium ulcerans strains isolated from Buruli ulcer (BU) lesion specimen has revealed a very limited genetic diversity of closely related isolates and a striking association between ...
Aboagye, Samuel+11 more
core +2 more sources
A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis. [PDF]
BACKGROUND: Antibiotic therapy targeting chronic mycobacterial disease is often ineffective due to problems with the emergence of drug resistance and non-replicating persistent intracellular antibiotic resistant phenotypes.
Bull, TJ+3 more
core +3 more sources