Interleukin‐24: A Multidimensional Therapeutic for Treatment of Human Diseases
The discovery of interleukin (IL)‐24 and studying its biological activity demonstrate its potential to serve as a therapeutic for human diseases, especially for cancer treatment. Image created with BioRender.com. ABSTRACT The field of targeted therapy exploits the selective expression of therapeutic genes or proteins in diseased cells.
Rajeswari Raguraman+2 more
wiley +1 more source
A case of Mycobacterium bovis infection is described in a death adult female wild boar in the province of Avellino, Campania Region (Southern Italy).
Emanuela Sannino+10 more
doaj
Thermal Death Time Curve of Mycobacterium tuberculosis var. bovis in Artificially Infected Milk [PDF]
H. R. Kells, S. A. Lear
openalex +2 more sources
Elusive preferred hosts or nucleic acid level selection? A commentary on: Evolutionary interpretations of mycobacteriophage biodiversity and host-range through the analysis of codon usage bias (Esposito et al. 2016) [PDF]
While confirming the long held view that viruses do not closely imitate the use of their host's codon catalogue, Esposito and coworkers nevertheless consider it surprising that, despite having the ability to infect the same host, many mycobacteriophages share little or no genetic similarity (i.e.
arxiv
Proposing a two-step Decision Support System (TPIS) based on Stacked ensemble classifier for early and low cost (step-1) and final (step-2) differential diagnosis of Mycobacterium Tuberculosis from non-tuberculosis Pneumonia [PDF]
Background: Mycobacterium Tuberculosis (TB) is an infectious bacterial disease presenting similar symptoms to pneumonia; therefore, differentiating between TB and pneumonia is challenging. Therefore, the main aim of this study is proposing an automatic method for differential diagnosis of TB from Pneumonia.
arxiv
New Insights into Mycobacterium bovis Prevalence in Wild Mammals in Portugal.
A survey to determine the prevalence of Mycobacterium bovis in wild mammals in Portugal was conducted by testing samples from hunted animals and those found dead between 2009 and 2013. In this study, we investigated 2116 wild mammals.
Ana Catarina Matos+5 more
semanticscholar +1 more source
ABSTRACT Mycobacterium fortuitum mycobacteremia and arthritis were diagnosed in a Briard dog from northern California. The dog was evaluated for lameness and had a history of immunosuppressive treatment and splenectomy for refractory immune thrombocytopenia.
Tianjiao Li+5 more
wiley +1 more source
Genetic diversities and drug resistance in Mycobacterium bovis isolates from zoonotic tuberculosis using whole genome sequencing. [PDF]
Background Zoonotic human tuberculosis (TB) caused by Mycobacterium bovis (M. bovis) is as vital as Mycobacterium tuberculosis, however with scarce available information.
Soliman NS+5 more
europepmc +2 more sources
Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap+10 more
wiley +1 more source
Mycobacterium bovis Infection in Humans and Cats in Same Household, Texas, USA, 2012
Mycobacterium bovis infection of cats is exceedingly rare in regions where bovine tuberculosis is not endemic. We describe the diagnosis and clinical management of pulmonary M. bovis infection in 2 indoor-housed cats and their association with at least 1
Kira E.F. Ramdas+5 more
doaj +1 more source