Chronic mycobacterial meningitis due to Mycobacterium chelonae: a case report
We report a case of chronic meningitis due to Mycobacterium chelonae. This organism is a rapidly growing Mycobacterium (RGM) and can be found worldwide in environmental sources such as soil, dust, and water. M. chelonae is an uncommon cause of meningitis;
Shokrallah Salmanzadeh +6 more
doaj +1 more source
Animal welfare and food safety: danger, risk and the distribution of responsibility [PDF]
Increased animal welfare may pose risks for public health, such as increased bacterial, viral or parasitic infections or an increased level of environmental contaminants in the food product.
Bos, Dr. Bram, Kijlstra, Prof.Dr. Aize
core
Deuteration of Six‐Membered N‐Heteroarenes: Chemistry and Applications
Deuterated six‐membered N‐Heteroarenes (6NHetAr) are finding utility in an increasing repertoire of applications. Our paper comprehensively reviews synthetic approaches that have been reported for the deuteration of 6NHetAr and their fused counterparts while providing an overview of established and emerging applications for these materials.
Liju Raju +4 more
wiley +1 more source
An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice [PDF]
Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes. FHA domains have been best characterized in eukaryotic signaling pathways but have been identified in six
Buxton, RS +8 more
core +2 more sources
Molecular docking shows that ligands 8 (a–i) adopt a U‐shaped geometry in the InhA active site, enabling stronger interactions than 7 (j–r). Surprisingly, both sets display similar potency, indicating that factors like electronic effects or solvation also influence anti‐TB activity.
Mukanda Gedeon Kadima +10 more
wiley +1 more source
Phage Therapy of Mycobacterium Infections: Compassionate Use of Phages in 20 Patients With Drug-Resistant Mycobacterial Disease. [PDF]
Dedrick RM +34 more
europepmc +1 more source
Status and potential of bacterial genomics for public health practice : a scoping review [PDF]
Background: Next-generation sequencing (NGS) is increasingly being translated into routine public health practice, affecting the surveillance and control of many pathogens.
Boon, Nele AM +6 more
core +2 more sources
Stimulation of Nonspecific Resistance to Infection by a Crude Cell Wall Preparation from Mycobacterium phlei [PDF]
Alfred E. Fox +4 more
openalex +1 more source
Synthesis of a Conformationally Fixed Bicyclomarin Derivative
The synthesis of a new bicyclic derivative of cyclomarin is described. Cyclomarin is a marine cyclopeptide with excellent antituberculosis activity. The synthesis of the linear heptapeptide and the two macrolactamizations proceed smoothly. Based on an X‐ray structure of cyclomarin bound to ClpC1, a new conformationally fixed, bicyclic cyclomarin ...
Jennifer Greve +2 more
wiley +1 more source
An observational prospective study of topical acidified nitrite for killing methicillin-resistant Staphylococcus aureus (MRSA) in contaminated wounds [PDF]
Background Endogenous nitric oxide (NO) kills bacteria and other organisms as part of the innate immune response. When nitrite is exposed to low pH, NO is generated and has been used as an NO delivery system to treat skin infections.
A Ghaffari +30 more
core +4 more sources

