Results 101 to 110 of about 210,851 (310)

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

open access: yesChemPlusChem, EarlyView.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

Non-tuberculous mycobacteria enhance the tryptophan-kynurenine pathway to induce immunosuppression and facilitate pulmonary colonization

open access: yesFrontiers in Cellular and Infection Microbiology
The increasing prevalence of non-tuberculous mycobacterium (NTM) infections alongside tuberculosis (TB) underscores a pressing public health challenge. Yet, the mechanisms governing their infection within the lung remain poorly understood.
Longjie Li   +11 more
doaj   +1 more source

The Zebrafish Breathes New Life into the Study of Tuberculosis

open access: yesFrontiers in Immunology, 2016
Tuberculosis (TB) is a global health emergency. Up to one third of the world’s population is infected with Mycobacterium tuberculosis, and the pathogen continues to kill almost two million people annually. Currently, the means for preventing, diagnosing,
Henna eMyllymäki   +5 more
doaj   +1 more source

Extensive infection of face by mycobacterium chelonae: An unusual presentation

open access: yesIndian Journal of Dermatology, 2014
Mycobacterium chelonae is a rapidly growing mycobacteria, causes cutaneous, soft tissue, and rarely lung infections. Here we present a rare case of extensive infection of face at multiple sites by Mycobacterium chelonae, with an unusual presentation ...
Swapna A Mali   +3 more
doaj   +1 more source

Molecular analysis of Mycobacterium tuberculosis DNA from a family of 18th century Hungarians [PDF]

open access: yes, 2003
The naturally mummified remains of a mother and two daughters found in an 18th century Hungarian crypt were analysed, using multiple molecular genetic techniques to examine the epidemiology and evolution of tuberculosis.
Donoghue, H.D.   +4 more
core  

Host Long Noncoding RNAs as Key Players in Mycobacteria–Host Interactions

open access: yesMicroorganisms
Mycobacterial infections, caused by various species within the Mycobacterium genus, remain one of the main challenges to global health across the world.
Stephen K. Kotey   +4 more
doaj   +1 more source

Interaction of mycobacterium tuberculosis with the host cells: a focus in the molecular mechanism involved in trafficking and autophagy [PDF]

open access: yes, 2018
Tuberculosis (TB) is an ancient disease remaining a serious health threat worldwide. It is caused by Mycobacterium tuberculosis (Mtb), an acid-fast bacilli, non-sporulated, slow-growing, immobile and aerobic.
Colombo, Maria Isabel   +2 more
core  

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