Results 21 to 30 of about 187,712 (288)
The genetic determinants of Mycobacterium leprae resistance to antimicrobial drugs [PDF]
Vestnik Dermatologii i Venerologii, 2021 The review is devoted to the appearance of resistance of a slowly developing disease leprosy to antimicrobial therapy (AMP), primarily recommended by the World Health Organization.
Dmitry A. Verbenko +3 more
doaj +1 more source
Microbiology Spectrum, 2022 Leprosy is caused by Mycobacterium leprae and Mycobacterium lepromatosis. We report construction and analyses of the complete genome sequence of M. lepromatosis FJ924.
Francisco J. Silva +4 more
doaj +1 more source
Mycobacterium leprae on Palatine Tonsils and Adenoids of Asymptomatic Patients, Brazil
Emerging Infectious Diseases, 2020 We investigated palatine tonsil and adenoid specimens excised from otorhinolaryngological patients in a leprosy-endemic region of Brazil. Fite-Faraco staining identified Mycobacterium spp. in 9 of 397 specimen blocks.
Marilda Aparecida Milanez Morgado de Abreu +4 more
doaj +1 more source
Mycobacterium leprae Infection in Ticks and Tick-Derived Cells
Frontiers in Microbiology, 2021 Leprosy is a zoonosis in the southern United States involving humans and wild armadillos. The majority of patients presenting with zoonotic strains of Mycobacterium leprae note extensive outdoor activity but only rarely report any history of direct ...
Natthida Tongluan +12 more
doaj +1 more source
Multi-omic detection of Mycobacterium leprae in archaeological human dental calculus
Philosophical Transactions of the Royal Society of London. Biological Sciences, 2020 Mineralized dental plaque (calculus) has proven to be an excellent source of ancient biomolecules. Here we present a Mycobacterium leprae genome (6.6-fold), the causative agent of leprosy, recovered via shotgun sequencing of sixteenth-century human ...
A. Fotakis +12 more
semanticscholar +1 more source
Health Science Journal of Indonesia, 2020 Latar belakang: Lepra merupakan penyakit yang disebabkan oleh Mycobacterium leprae. Resistensi obat merupakan salah satu tantangan dalam pemberantasan kusta khususnya di Papua.
Yustinus Maladan +3 more
doaj +1 more source
Frontiers in Microbiology, 2020 Mycobacterium leprae, the causative agent of leprosy, is an unculturable bacterium with a considerably reduced genome (3.27 Mb) compared to homologues mycobacteria from the same ancestry. In 2001, the genome of M.
M. Tió-Coma +12 more
semanticscholar +1 more source
Ultra-sensitive detection of Mycobacterium leprae: DNA extraction and PCR assays
PLoS Neglected Tropical Diseases, 2020 Leprosy urgently needs a precise and early diagnostic tool. The sensitivity of the direct (bacilli staining, Mycobacterium leprae DNA) and indirect (antibody levels, T cell assays) diagnostics methods vary based on the clinical form.
F. Manta +10 more
semanticscholar +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2008 O diagnóstico da hanseníase se baseia em manifestações clínicas e não existe teste laboratorial para diagnosticar casos assintomáticos ou para prever progressão da doença entre indivíduos expostos.
Mariane Martins de Araújo Stefani
doaj +1 more source
Myelin breakdown favours Mycobacterium leprae survival in Schwann cells
Cellular Microbiology, 2020 Leprosy neuropathy is a chronic degenerative infectious disorder of the peripheral nerve caused by the intracellular obligate pathogen Mycobacterium leprae (M. leprae).
B. S. Mietto +4 more
semanticscholar +1 more source