Results 51 to 60 of about 14,244 (229)

Assessment of Healthcare Professionals' Knowledge Regarding Nontuberculosis Mycobacterial Infections at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2024: A Cross‐Sectional Study

Journal of Clinical Laboratory Analysis, EarlyView.
A comprehensive and schematic illustration of the study's methods and materials. ABSTRACT Background Nontuberculosis mycobacteria (NTM) are environmental pathogens that can cause pulmonary infections, especially among the immunocompromised population. There is limited research on healthcare professionals' knowledge of NTM infections in Ethiopia.
Teklehaimanot Kiros, Mulat Erkihun, Bekele Sharew, Andargachew Almaw, Ayenew Assefa, Tegenaw Tiruneh, Birhanu Getie, Yenealem Solomon, Shewaneh Damtie   +8 more
wiley   +1 more source

Cultivation of Mycobacterium Leprae

Experimental Biology and Medicine, 1933
McKinley and Soule1 reported the successful cultivation of Mycobacterium leprae, obtained from Puerto Rican lepers, on several culture media. Subsequent reports were made by Soule and McKinley2, 3 when their nonchromogenic strain of acid-fast bacilli, believed to be the true Mycobacterium leprae, had been carried through the eighth and sixteenth ...
Elizabeth Verder, Earl B. McKinley
openaire   +2 more sources

Evaluating the Benefits and Limits of Multiple Displacement Amplification With Whole‐Genome Oxford Nanopore Sequencing

Molecular Ecology Resources, EarlyView.
ABSTRACT Multiple displacement amplification (MDA) outperforms conventional PCR in long fragment and whole‐genome amplification, making it attractive to couple MDA with long‐read sequencing of samples with limited quantities of DNA to obtain improved genome assemblies.
Fiifi Agyabeng‐Dadzie, Megan S. Beaudry, Alex Deyanov, Haley Slanis, Minh Q. Duong, Randi Turner, Asis Khan, Cesar A. Arias, Jessica C. Kissinger, Travis C. Glenn, Rodrigo de Paula Baptista   +10 more
wiley   +1 more source

Macrophages and autophagy: partners in crime

The FEBS Journal, EarlyView.
Autophagy is a key regulator of macrophage function, influencing critical processes like polarization, cytokine secretion, and phagocytosis. Its impact on macrophage behavior varies across different tissues and disease contexts, where it can either promote protective responses or contribute to detrimental outcomes, depending on the physiological or ...
Alessandra Vitaliti, Alessio Reggio, Alessandro Palma   +2 more
wiley   +1 more source

M. leprae inhibits apoptosis in THP-1 cells by downregulation of Bad and Bak and upregulation of Mcl-1 gene expression

BMC Microbiology, 2006
Background Virulent Mycobacterium leprae interfere with host defense mechanisms such as cytokine activation and apoptosis. The mitochondrial pathway of apoptosis is regulated by the Bcl-2 family of proteins.
Tayyebi Ali, Ashraf Mussarat, Hasan Zahra, Hussain Rabia   +3 more
doaj   +1 more source

From leprosy to ground zero: Imagining futures in a world of elimination

Medical Anthropology Quarterly, EarlyView.
Abstract Achieving a target of zero—zero disease, zero disability, and zero discrimination—has become the dominant focus of campaigns to control or eliminate diseases, from HIV/AIDS to malaria to leprosy. Given the historical failure of most eradication programs over the last century, such teleological imaginings of disease‐free futures might seem ...
James Staples
wiley   +1 more source

A novel approach for feline sporotrichosis pathogen detection based on loop‐mediated isothermal amplification

Veterinary Dermatology, EarlyView.
Background – Sporotrichosis is a chronic, mycotic infection caused by fungi of the genus Sporothrix. Zoonotic sporotrichosis occurs mainly through S. brasiliensis transmission, resulting from the organism's traumatic introduction via scratches or bites, or contact with exudate from contaminated cats.
Steffanie Amadei, Júlia Campos, Amanda Bertão‐Santos, Alis Frentzel, Hugo Ávila, Fabiana S. Monti, Marconi R. Farias   +6 more
wiley   +1 more source

A Mycobacterium leprae VNTR database [PDF]

Leprosy Review, 2010
A great deal of the last quarter of a century’s astonishing progress in understanding and treating human disease is attributable to the existence of public databases where information about DNA sequences, protein sequences, protein structures, human variation, etc. is stored and is freely available to all interested investigators.
openaire   +2 more sources

Non-tuberculous mycobacteria infection presenting as a hepatic allograft abscess

IDCases, 2023
Nontuberculous mycobacteria (NTM) are mycobacterial species other than Mycobacterium tuberculous and Mycobacterium leprae [1]. They are environmental organisms which have been implicated in a wide array of clinical syndromes. Here we describe a case of a
Anthony Robateau Colón, Eibhlin Higgins, Nicholas Boire, Nathan Cummins, Kymberly D. Watt   +4 more
doaj  

Structural Properties of an S-system Model of Mycobacterium Tuberculosis Gene Regulation [PDF]

arXiv, 2020
Magombedze and Mulder in 2013 studied the gene regulatory system of Mycobacterium Tuberculosis (Mtb) by partitioning this into three subsystems based on putative gene function and role in dormancy/latency development. Each subsystem, in the form of S-system, is represented by an embedded chemical reaction network (CRN), defined by a species subset and ...
arxiv