Results 51 to 60 of about 26,609 (224)

Acidic pH Restricts Non‐Tuberculous Mycobacteria Replication

Molecular Microbiology, EarlyView.
Different nontuberculous mycobacteria (NTM) species display unique replication profiles in acidic pH in vitro which correlates to their replication within human macrophages. Inhibition of the acidic environments within the macrophage enhances bacterial viability emphasising the role of acidic pH during NTM infections.
Parise K. Lockwood, Luiz Pedro Sorio de Carvalho, Rachel P. J. Lai, Maximiliano G. Gutierrez   +3 more
wiley   +1 more source

Salivary anti-PGL-1 IgM may indicate active transmission of Mycobacterium leprae among young people under 16 years of age

Brazilian Journal of Infectious Diseases, 2017
Considering that the main route of Mycobacterium leprae transmission is the upper respiratory tract, detection of salivary antibodies can be a useful tool for diagnosing early infection.
Alexandre Casimiro de Macedo, José Evandro Cunha, Jr., Juliana Navarro Ueda Yaochite, Clodis Maria Tavares, Aparecida Tiemi Nagao-Dias   +4 more
doaj   +1 more source

Multiplex PCR technique could be an alternative approach for early detection of leprosy among close contacts - a pilot study from India [PDF]

, 2010
Background Implementation of Multi drug Therapy (MDT) regimen has resulted in the decline of the total number of leprosy cases in the world.
Surajita Banerjee, Kamalesh Sarkar, Soma Gupta, Prasanta Sinha Mahapatra, Siddhartha Gupta, Samudra Guha, Debasis Bandhopadhayay, Chaitry Ghosal, Suman Kalyan Paine, Rathindra Nath Dutta, Nibir Biswas, Basudev Bhattacharya   +11 more
core   +2 more sources

Perceptions of Hansen's Disease in Northeast Brazil: A Community‐Based Study Integrating Stigma, Empowerment, and Social Distance

Tropical Medicine &International Health, EarlyView.
ABSTRACT Perceptions of Hansen’s disease (HD) can influence the level of stigma, empowerment, and intention to distance oneself from those affected by the disease. Knowledge, attitudes, and beliefs shape these perceptions. This study aims to understand perceptions of HD regarding stigma and empowerment. Method: A cross‐sectional, mixed‐methods research
Jaqueline Caracas Barbosa, Aymée Medeiros da Rocha, Hellen Xavier Oliveira, Nágila Nathaly Lima Ferreira, Adriana da Silva dos Reis, Anderson Fuentes Ferreira, Wim H. van Brakel, Anna T. van ‘t Noordende, Duane Charles Hinders, José Alexandre Menezes da Silva, Carmem Emmanuely Leitão Araújo, Rômulo do Nascimento Rocha, Alberto Novaes Ramos Jr   +12 more
wiley   +1 more source

BCG and adverse events in the context of leprosy [PDF]

, 2018
Background: Notwithstanding its beneficial immunoprophylactic outcomes regarding leprosy and childhood TB, BCG vaccination may cause adverse events, particularly of the skin.
Annemieke Geluk, Anouk van Hooij, Jan Hendrik Richardus, Korshed Alam, Louis Wilson, Renate Richardus, Renate Richardus, Susan J. F. van den Eeden   +7 more
core   +4 more sources

Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017

Emerging Infectious Diseases, 2020
Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to ...
Qingtian Guan, Talal S. Almutairi, Tahani Alhalouli, Arnab Pain, Faisal Alasmari   +4 more
doaj   +1 more source

Modulation of the Response to Mycobacterium leprae and Pathogenesis of Leprosy

Frontiers in Microbiology, 2022
The initial infection by the obligate intracellular bacillus Mycobacterium leprae evolves to leprosy in a small subset of the infected individuals. Transmission is believed to occur mainly by exposure to bacilli present in aerosols expelled by infected ...
Natasha Cabral, Vilma de Figueiredo, Mariana Gandini, Cíntia Fernandes de Souza, Rychelle Affonso Medeiros, Letícia Miranda Santos Lery, Flávio Alves Lara, Cristiana Santos de Macedo, Maria Cristina Vidal Pessolani, Geraldo Moura Batista Pereira   +9 more
doaj   +1 more source

Length, Protein-Protein Interactions, and Complexity

, 2004
The evolutionary reason for the increase in gene length from archaea to prokaryotes to eukaryotes observed in large scale genome sequencing efforts has been unclear.
Albert, Bateman, Bates, Bates, Boeckmann, Carlson, Daan Frenkel, Eisenhaber, Hasty, Hopkins, Jeong, Jeong, Lander, Mewes, Michael W. Deem, Mott, Prost, Rhines, Riddle, Steinmetz, Strausberg, Taison Tan, Uetz, Vishal Gupta, Watts, Waxman, Zhang, Zhang   +27 more
core   +1 more source

Type 2 Lepra Reaction Following Antituberculosis Treatment Initiation in an Elderly Male With Coexisting Hansen's Disease: A Case Report

Respirology Case Reports, Volume 14, Issue 3, March 2026.
We report a case of a man developing erythema nodosum leprosum after initiating treatment for drug‐susceptible pulmonary tuberculosis. This highlights the importance of recognising concomitant leprosy in patients with tuberculosis since these mycobacterial infections require different long‐term multidrug regimens.
Cary Amiel G. Villanueva, Ysabel Regina H. Ortiz, Winlove P. Mojica, Albert B. Albay Jr   +3 more
wiley   +1 more source

Faktor-Faktor yang Mempengaruhi Terjadinya Infeksi Kusta

JKS (Jurnal Kedokteran Syiah Kuala), 2010
Abstrak.  Program pemberantasan kusta di dunia telah berjalan Jebih dari 20 tahun terakhir, namun kasus insiden kusta baru tidak menurun. Dengan kata lain penularan penyakit kusta masih terus terjadi di rnana- mana.
Mudatsir Mudatsir
doaj