Results 51 to 60 of about 14,313 (203)
Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017
Emerging Infectious Diseases, 2020 Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to ...
Qingtian Guan +4 more
doaj +1 more source
Veterinary Dermatology, EarlyView.Background – Sporotrichosis is a chronic, mycotic infection caused by fungi of the genus Sporothrix. Zoonotic sporotrichosis occurs mainly through S. brasiliensis transmission, resulting from the organism's traumatic introduction via scratches or bites, or contact with exudate from contaminated cats.
Steffanie Amadei +6 more
wiley +1 more source
The Role of Foxes in Transmitting Zoonotic Bacteria to Humans: A Scoping Review
Zoonoses and Public Health, EarlyView.ABSTRACT Zoonotic diseases inflict substantial burdens on human and animal populations worldwide, and many of these infections are bacterial. An Australian study investigating environmental risk factors for Buruli ulcer in humans detected the causative agent, Mycobacterium ulcerans, in the faeces of wild foxes, a novel finding that suggests foxes may ...
Emma C. Hobbs +6 more
wiley +1 more source
Molecular Ecology Resources, Volume 25, Issue 6, August 2025.ABSTRACT Multiple displacement amplification (MDA) outperforms conventional PCR in long fragment and whole‐genome amplification, making it attractive to couple MDA with long‐read sequencing of samples with limited quantities of DNA to obtain improved genome assemblies.
Fiifi Agyabeng‐Dadzie +10 more
wiley +1 more source
The Activity of a Thiadiazole on Mycobacterium leprae
Experimental Biology and Medicine, 1976 SummaryA new broad-spectrum antimicrobial, 2-amino-5-(l-methyl-5-nitro-2-imi-dazolyl)-1,3,4-thiadiazole, reported inactive against Mycobacterium tuberculosis, inhibited multiplication of M. leprae in the mouse foot pad when administered orally to the mice.
openaire +3 more sources
Is Mycobacterial InhA a Suitable Target for Rational Drug Design?
ChemMedChem, Volume 20, Issue 13, July 1, 2025.InhA is the target of isoniazid, a first‐line antituberculosis drug. Isoniazid is, in fact, a prodrug that needs to be activated. Researchers are trying to develop direct inhibitors of InhA. This includes the resolution of crystallographic structures. The Protein Data Bank contains over a hundred InhA structures.
Julien Rizet +7 more
wiley +1 more source
Mycobacterial genomics and structural bioinformatics: opportunities and challenges in drug discovery
Emerging Microbes and Infections, 2019 Of the more than 190 distinct species of Mycobacterium genus, many are economically and clinically important pathogens of humans or animals. Among those mycobacteria that infect humans, three species namely Mycobacterium tuberculosis (causative agent of ...
Vaishali P. Waman +7 more
doaj +1 more source
Studies of Lipoproteins of Mycobacterium leprae
Japanese journal of leprosy, 2004 The deciphering of the genomic sequence of Mycobacterium leprae has made possible to predict the possible lipoproteins. The consensus sequence at the N-terminal region of the protein, including the cysteine residue to which the lipid moiety gets attached, provides a clue to the search.
Yumi Maeda +2 more
openaire +3 more sources
A rare case of lepromatous leprosy in Germany
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Roman Saternus +8 more
wiley +1 more source
Beyond Elimination: Unveiling Leprosy Cases in Far West Nepal
Clinical Case Reports, Volume 13, Issue 6, June 2025.ABSTRACT Leprosy, one of the Neglected Tropical Diseases (NTDs), can be diagnosed based on any of its three characteristics: a hypopigmented or reddish skin patch with sensory loss, thickened peripheral nerves with sensory impairment, and a positive skin smear for acid‐fast bacilli (AFB).
Smriti Lama Thing +5 more
wiley +1 more source