Results 1 to 10 of about 669,788 (215)

Mycobacterium tuberculosis Dissemination Plays a Critical Role in Pathogenesis

Frontiers in Cellular and Infection Microbiology, 2020
Mycobacterium tuberculosis is primarily a respiratory pathogen. However, 15% of infections worldwide occur at extrapulmonary sites causing additional complications for diagnosis and treatment of the disease. In addition, dissemination of M.
G Callea, Jeffrey D Cirillo
exaly   +2 more sources

Immune evasion and provocation by Mycobacterium tuberculosis

Nature Reviews Microbiology, 2022
Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host immune response and be transmitted to uninfected individuals.
P. Chandra, Steven J. Grigsby, J. Philips   +2 more
semanticscholar   +1 more source

Pathogenicity and virulence of Mycobacterium tuberculosis

Virulence, 2022
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious disease with one of the highest morbidity and mortality rates worldwide.
Kathryn C. Rahlwes, B. Dias, Priscila C. Campos, Samuel Álvarez-Arguedas, M. Shiloh   +4 more
semanticscholar   +1 more source

Anti-Mycobacterial Drug Resistance in Japan: How to Approach This Problem?

Antibiotics, 2021
Mycobacteriosis is mainly caused by two groups of species: Mycobacterium tuberculosis and non-tuberculosis mycobacteria (NTM). The pathogens cause not only respiratory infections, but also general diseases.
Keisuke Kamada, Satoshi Mitarai
doaj   +1 more source

Toward a Phage Cocktail for Tuberculosis: Susceptibility and Tuberculocidal Action of Mycobacteriophages against Diverse Mycobacterium tuberculosis Strains

mBio, 2021
Tuberculosis kills 1.5 million people each year, and resistance to commonly used antibiotics contributes to treatment failures. The therapeutic potential of bacteriophages against Mycobacterium tuberculosis offers prospects for shortening antibiotic ...
Carlos A. Guerrero-Bustamante, R. Dedrick, R. Garlena, D. Russell, G. Hatfull   +4 more
semanticscholar   +1 more source

Potential Cross-Transmission of Mycobacterium abscessus among Non-Cystic Fibrosis Patients at a Tertiary Hospital in Japan

Microbiology Spectrum, 2022
Mycobacterium abscessus (M. abscessus) is a highly antimicrobial-resistant pathogen that causes refractory pulmonary disease. Recently, the possibility of M. abscessus cross-transmission among cystic fibrosis (CF) patients has been reported.
Keiji Fujiwara, Mitsunori Yoshida, Yoshiro Murase, Akio Aono, Koji Furuuchi, Yoshiaki Tanaka, Ken Ohta, Manabu Ato, Satoshi Mitarai, Kozo Morimoto   +9 more
doaj   +1 more source

Isolation of Mycobacterium talmoniae from a patient with diffuse panbronchiolitis: a case report

BMC Infectious Diseases, 2021
Background Mycobacterium (M) talmoniae isolated from a patient with cystic fibrosis was first described in 2017, and cases of M. talmoniae remain exceedingly rare. Case presentation A 51-year-old woman had respiratory symptoms for 10 years.
Tomoko Suzuki, Miwako Saitou, Yuriko Igarashi, Satoshi Mitarai, Katsunao Niitsuma   +4 more
doaj   +1 more source

A sister lineage of the Mycobacterium tuberculosis complex discovered in the African Great Lakes region

Nature Communications, 2020
The human- and animal-adapted lineages of the Mycobacterium tuberculosis complex (MTBC) are thought to have expanded from a common progenitor in Africa. However, the molecular events that accompanied this emergence remain largely unknown.
J. Ngabonziza, Chloé Loiseau, M. Marceau, Agathe Jouet, Fabrizio Menardo, O. Tzfadia, R. Antoine, Esdras Belamo Niyigena, W. Mulders, Kristina Fissette, M. Diels, C. Gaudin, S. Duthoy, W. Ssengooba, E. André, M. Kaswa, Y. Habimana, D. Brites, D. Affolabi, J. Mazarati, B. D. de Jong, L. Rigouts, S. Gagneux, C. Meehan, P. Supply   +24 more
semanticscholar   +1 more source

Molecular Epidemiological Characteristics of Mycobacterium abscessus Complex Derived from Non-Cystic Fibrosis Patients in Japan and Taiwan

Microbiology Spectrum, 2022
Mycobacterium abscessus complex (MABC) is a group of emerging, highly antimicrobial-resistant non-tuberculous mycobacteria. Specific MABC clones are spreading globally in patients with cystic fibrosis (CF); however, associated genomic epidemiology is ...
Mitsunori Yoshida, Jung-Yien Chien, Kozo Morimoto, Takeshi Kinjo, Akio Aono, Yoshiro Murase, Keiji Fujiwara, Yuta Morishige, Hiroaki Nagano, Ruwen Jou, Naoki Hasegawa, Manabu Ato, Yoshihiko Hoshino, Po-Ren Hsueh, Satoshi Mitarai   +14 more
doaj   +1 more source

Aortic endograft infection by Mycobacterium abscessus subsp. massiliense with acquired clarithromycin resistance: a case report

BMC Infectious Diseases, 2023
Background Mycobacterium abscessus subsp. massiliense (MMA) comprises a group of non-tuberculous, rapidly growing mycobacteria. Although MMA can cause pulmonary diseases, surgical site infections, and disseminated diseases, aortic endograft infection has
Yutaro Akiyama, Noriko Iwamoto, Keisuke Kamada, Atsushi Yoshida, Asami Osugi, Satoshi Mitarai, Tetsuya Suzuki, Kei Yamamoto, Maki Nagashima, Tetsuya Horai, Norio Ohmagari   +10 more
doaj   +1 more source