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Mycobacterium tuberculosis Dissemination Plays a Critical Role in Pathogenesis [PDF]

open access: goldFrontiers in Cellular and Infection Microbiology, 2020
Mycobacterium tuberculosis is primarily a respiratory pathogen. However, 15% of infections worldwide occur at extrapulmonary sites causing additional complications for diagnosis and treatment of the disease. In addition, dissemination of M.
Madeleine G. Moule, Jeffrey D. Cirillo
openalex   +2 more sources

Immune evasion and provocation by Mycobacterium tuberculosis

open access: yesNature Reviews Microbiology, 2022
Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host immune response and be transmitted to uninfected individuals.
Pallavi Chandra   +2 more
exaly   +2 more sources

Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues

open access: yesNature Reviews Microbiology, 2019
Conor J Meehan   +2 more
exaly   +2 more sources

Metabolic principles of persistence and pathogenicity in Mycobacterium tuberculosis

open access: yesNature Reviews Microbiology, 2018
Sabine Ehrt   +2 more
exaly   +2 more sources

Pathogenicity and virulence of Mycobacterium tuberculosis

open access: yesVirulence, 2022
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious disease with one of the highest morbidity and mortality rates worldwide.
Kathryn C. Rahlwes   +4 more
semanticscholar   +1 more source

Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis

open access: yesNature Communications, 2021
Tuberculosis is a chronic disease that displays several features commonly associated with biofilm-associated infections: immune system evasion, antibiotic treatment failures, and recurrence of infection. However, although Mycobacterium tuberculosis (Mtb)
Poushali Chakraborty   +4 more
semanticscholar   +1 more source

Anti-Mycobacterial Drug Resistance in Japan: How to Approach This Problem?

open access: yesAntibiotics, 2021
Mycobacteriosis is mainly caused by two groups of species: Mycobacterium tuberculosis and non-tuberculosis mycobacteria (NTM). The pathogens cause not only respiratory infections, but also general diseases.
Keisuke Kamada, Satoshi Mitarai
doaj   +1 more source

Potential Cross-Transmission of Mycobacterium abscessus among Non-Cystic Fibrosis Patients at a Tertiary Hospital in Japan

open access: yesMicrobiology Spectrum, 2022
Mycobacterium abscessus (M. abscessus) is a highly antimicrobial-resistant pathogen that causes refractory pulmonary disease. Recently, the possibility of M. abscessus cross-transmission among cystic fibrosis (CF) patients has been reported.
Keiji Fujiwara   +9 more
doaj   +1 more source

Toward a Phage Cocktail for Tuberculosis: Susceptibility and Tuberculocidal Action of Mycobacteriophages against Diverse Mycobacterium tuberculosis Strains

open access: yesmBio, 2021
Tuberculosis kills 1.5 million people each year, and resistance to commonly used antibiotics contributes to treatment failures. The therapeutic potential of bacteriophages against Mycobacterium tuberculosis offers prospects for shortening antibiotic ...
Carlos A. Guerrero-Bustamante   +4 more
semanticscholar   +1 more source

Causative antigens of humidifier lung in vapor from a humidifier: A case report

open access: yesRespiratory Medicine Case Reports, 2023
A 68-year-old man exhibited fever and cough three weeks prior to hospital admission after three months of ultrasonic humidifier usage. Chest computed tomography showed bilateral ground-glass opacities, lymphocyte levels in the bronchoalveolar lavage ...
Masafumi Shimoda   +8 more
doaj   +1 more source

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