Results 1 to 10 of about 484,514 (49)
Immune evasion and provocation by Mycobacterium tuberculosis
Nature Reviews Microbiology, 2022 Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host immune response and be transmitted to uninfected individuals.
P. Chandra +2 more
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mBio, 2021 Tuberculosis kills 1.5 million people each year, and resistance to commonly used antibiotics contributes to treatment failures. The therapeutic potential of bacteriophages against Mycobacterium tuberculosis offers prospects for shortening antibiotic ...
Carlos A. Guerrero-Bustamante +4 more
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Nature Communications, 2020 The human- and animal-adapted lineages of the Mycobacterium tuberculosis complex (MTBC) are thought to have expanded from a common progenitor in Africa. However, the molecular events that accompanied this emergence remain largely unknown.
J. Ngabonziza +24 more
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Mycobacterium tuberculosis Dissemination Plays a Critical Role in Pathogenesis
Frontiers in Cellular and Infection Microbiology, 2020 Mycobacterium tuberculosis is primarily a respiratory pathogen. However, 15% of infections worldwide occur at extrapulmonary sites causing additional complications for diagnosis and treatment of the disease. In addition, dissemination of M.
M. G. Moule, J. Cirillo
semanticscholar +1 more source
New England Journal of Medicine, 2018 BACKGROUND Recent Mycobacterium tuberculosis infection confers a predisposition to the development of tuberculosis disease, the leading killer among global infectious diseases.
E. Nemes +26 more
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The Immune Escape Mechanisms of Mycobacterium Tuberculosis
International Journal of Molecular Sciences, 2019 Epidemiological data from the Center of Disease Control (CDC) and the World Health Organization (WHO) statistics in 2017 show that 10.0 million people around the world became sick with tuberculosis.
Weijie Zhai +4 more
semanticscholar +1 more source
Mycobacterium tuberculosis infection of host cells in space and time
FEMS Microbiology Reviews, 2019 Tuberculosis (TB) caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb) remains one of the deadliest infectious diseases with over a billion deaths in the past 200 years (Paulson 2013).
Claudio Bussi, M. Gutierrez
semanticscholar +1 more source
Journal of Clinical Microbiology, 1997 Widespread use of DNA restriction fragment length polymorphism (RFLP) to differentiate strains of Mycobacterium tuberculosis to monitor the transmission of tuberculosis has been hampered by the need to culture this slow-growing organism and by the level ...
J. Kamerbeek +14 more
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Immunology of Mycobacterium tuberculosis Infections
Microbiology spectrum, 2019 Tuberculosis (TB) is a serious global public health challenge that results in significant morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium tuberculosis (M.
J. K. Sia, Jyothi Rengarajan
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Immune Response to Mycobacterium tuberculosis: A Narrative Review
Frontiers in Pediatrics, 2019 The encounter between Mycobacterium tuberculosis (Mtb) and the host leads to a complex and multifaceted immune response possibly resulting in latent infection, tubercular disease or to the complete clearance of the pathogen.
M. de Martino +3 more
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