Results 91 to 100 of about 692,714 (305)

The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis

mBio, 2017
The cell wall of Mycobacterium tuberculosis is composed of unique lipids that are important for pathogenesis. Indeed, the first-ever genetic screen in M. tuberculosis identified genes involved in the biosynthesis and transport of the cell wall lipid PDIM
Jeffrey Quigley, V. Hughitt, C. Velikovsky, Roy A. Mariuzza, N. El-Sayed, V. Briken   +5 more
semanticscholar   +1 more source

Drug Resistance in Mycobacterium tuberculosis

Mycobacterium - Research and Development, 2017
Tuberculosis (TB) remains to be a serious health problem worldwide. There is an increased transmission of Mycobacterium tuberculosis strains with drug resistance, hence complicat‐ ing TB control. The deciphering of the M.
K. Peñuelas-Urquides, F. Castorena-Torres, B. Silva-Ramírez, Mario Bermúdez de León   +3 more
semanticscholar   +1 more source

Extreme Drug Tolerance of Mycobacterium tuberculosis in Caseum

Antimicrobial Agents and Chemotherapy, 2017
Tuberculosis (TB) recently became the leading infectious cause of death in adults, while attempts to shorten therapy have largely failed. Dormancy, persistence, and drug tolerance are among the factors driving the long therapy duration. Assays to measure
Jansy P. Sarathy, L. Via, Danielle M. Weiner, L. Blanc, H. Boshoff, E. Eugenin, C. Barry, V. Dartois   +7 more
semanticscholar   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Phospholipase C in Beijing strains of Mycobacterium tuberculosis

Iranian Journal of Microbiology, 2010
Background and Objectives: Phospholipase of Mycobacterium tuberculosis plays an important role in pathogenesis through breaking up phospholipids and production of diacylglycerol.
H Goudarzi, ES Mirsamadi, S Jahani Sherafat, M Esfahani, N Faramarzi, P Farnia   +5 more
doaj  

An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection

Journal of Experimental Medicine, 1993
Tuberculosis, a major health problem in developing countries, has reemerged in recent years in many industrialized countries. The increased susceptibility of immunocompromised individuals to tuberculosis, and many experimental studies indicate that T ...
J. Flynn, J. Chan, Karla J. Triebold, D. Dalton, T. A. Stewart, B. Bloom   +5 more
semanticscholar   +1 more source

Evaluation of the cross-immunity between Mycobacterium tuberculosis and Mycobacterium abscessus in vitro

BMC Microbiology
Mycobacterium tuberculosis (M. tuberculosis) and Mycobacterium abscessus (M. abscessus) are important pathogens that can cause lung diseases. Given the abundance of shared antigens between these two pathogens, evaluating the cross-immunization between ...
Da Xu, Yujie Gu, Guilian Li, Ruihuan Wang, Shiqi Xiao, Hongyang Duan, Jingwei Jiang, Xiuqin Zhao, Kanglin Wan, Xinyue He, Haican Liu, Yongliang Lou   +11 more
doaj   +1 more source

Coinfection of Mycobacterium malmoense and Mycobacterium tuberculosis in a patient with acquired inmune deficiency syndrome

Revista Peruana de Medicina Experimental y Salud Pública, 2014
A case is presented of coinfection with Mycobacterium malmoense and Mycobacterium tuberculosis in a Cuban patient with AIDS which produced respiratory and liver disease respectively.
Lilian María Mederos Cuervo, Angélica Reyes Pérez, Lidunka Valdes Alonso, Francisco Rodríguez Delgado, Misleydis Sardiñas Aragón, María Rosarys Martínez Romero, Raúl Díaz Romero   +6 more
doaj   +1 more source

Homocitrullinated Peptides Drive Pro‐Inflammatory T Cell Responses in a Humanized Mouse Model of Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Anti‐homocitrullinated protein/peptide antibodies are specific to rheumatoid arthritis (RA) and predictive of worse prognosis, suggesting a pathogenic role for autoreactivity to homocitrullinated peptides (HomoCitP). However, T cell responses to HomoCitP remain largely unexplored.
Sofya Ulanova, Jaspreet Kaur, Gabrielle Buckley, S. M. Mansour Haeryfar, Lisa Cameron, Ewa Cairns, Lillian Barra   +6 more
wiley   +1 more source

Nontuberculosis Mycobacteria: Isolation from clinical samples in Iraq

International Journal of Mycobacteriology, 2016
Objective/background: Nontuberculosis mycobacteria (NTM), defined as any mycobacterial strain other than Mycobacterium tuberculosis complex, are a diverse group of pathogens that cause a substantive, but often unappreciated worldwide burden of illness ...
Shatha T Ahmed, Ahmed A Alsudani, Ruqaya M Ali, Batool A Shihab, Sana A Hussein   +4 more
doaj   +1 more source