Results 121 to 130 of about 380,966 (308)

Molecular analysis of Mycobacterium tuberculosis DNA from a family of 18th century Hungarians [PDF]

, 2003
The naturally mummified remains of a mother and two daughters found in an 18th century Hungarian crypt were analysed, using multiple molecular genetic techniques to examine the epidemiology and evolution of tuberculosis.
Donoghue, H.D., Fletcher, H.A., Spigelman, M., Taylor, G.M., van der Zanden, A.G.M.   +4 more
core  

Snapshots of Motion: A Novel Structural Intermediate Reveals Conserved Dynamics in Archaeal DNA Ligases

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas, E. Flores‐Hernández, C. Cardona‐Félix, E. Rudiño‐Piñera   +3 more
wiley   +1 more source

Tirap controls Mycobacterium tuberculosis phagosomal acidification

, 2023
Imène Belhaouane, Amine Pochet, Jonathan Chatagnon, Eik Hoffmann, Christophe J. Queval, Nathalie Deboosère, Céline Boidin‐Wichlacz, Laleh Majlessi, Valentin Sencio, Séverine Heumel, Alexandre Vandeputte, Elisabeth Werkmeister, Laurence Fiévez, Fabrice Bureau, Yves Rouillé, François Trottein, Mathias Chamaillard, Priscille Brodin, Arnaud Machelart   +18 more
openalex   +2 more sources

Diagnóstico bacteriológico de tuberculosis renal: experiencia del Laboratorio Regional de Tuberculosis de la provincia de Córdoba

Revista Argentina de Microbiología, 2011
Dada la considerable incidencia de tuberculosis renal entre enfermos con tuberculosis pulmonar, nos propusimos estudiar la frecuencia de esta asociación en pacientes atendidos en centros de salud públicos y privados de Córdoba a lo largo del período 1997-
Mariana Berta, Gabriela Sturm, Leticia Juri, Maria C Cosiansi, Silvia Barzón, Ana I Barnes, Silvia C Rojo   +6 more
doaj  

Roles of transcription factors, RBPA and SIGF, in the mycobacterium tuberculosis [PDF]

, 2016
The mechanism of prokaryotic transcription has been characterized primarily in the classic system, Escherichia coli, and cannot be confidently extended to include other prokaryotic species, such as those of the Actinobacteria phylum.
Pope, Steven Scott
core   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Deciphering the Heterogeneity of Pulmonary Macrophages in Response to Fine Particles

Small, EarlyView.
This study introduces a dual‐labeled gold nanoparticle model to capture particle–responsive cells via integrating fluorescence‐activated cell sorting and single‐cell RNA sequencing. Fourteen macrophage subsets are identified with response and function heterogeneity, among which AMs_3, AMs_7, and recMacs_4 subsets show stronger phagocytic activation ...
Qing'e Shan, Zheng Dong, Ning Li, Zijie Zhou, Jiayu Ren, Wei Liu, Feng Xu, Yu Qi, Juan Ma, Yi Liu, Shuping Zhang, Sijin Liu   +11 more
wiley   +1 more source

Proteomic Profiling of Alveolar Macrophages Identifies Loss of Lysosomal Content as an Indicator of Nanofiber‐Induced Frustrated Phagocytosis

Small, EarlyView.
This proteomic study examines how nanofibers affect lung macrophages by analyzing protein changes following exposure to various fibrous materials. Nanofibers triggered the release of inflammatory enzymes, and importantly, lysosomal content release was identified as an early event associated with frustrated phagocytosis. Seventeen sensitive and relevant
Tobias Stobernack, Antje Vennemann, Carla Ribalta, Julia Schendel, Oliver Gräb, Rico Ledwith, Mario Pink, Andrea Haase, Martin Wiemann, Verónica I. Dumit   +9 more
wiley   +1 more source

Unsupported planar lipid membranes formed from mycolic acids of Mycobacterium tuberculosis [PDF]

, 2010
Kyle W. Langford, Boyan Penkov, Ian M. Derrington, Jens H. Gundlach   +3 more
openalex   +1 more source

Efficient 5-OP-RU-induced enrichment of Mucosal-associated invariant T cells in the murine lung does not enhance control of aerosol Mycobacterium tuberculosis infection [PDF]

, 2020
Charles Kyriakos Vorkas, Olivier Levy, Miroslav Skular, Kelin Li, Jeffrey Aubé, Michael S. Glickman   +5 more
openalex   +1 more source