Results 171 to 180 of about 382,621 (326)

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Virulence of Mycobacterium tuberculosis [PDF]

, 1985
John M. Grange
openalex   +1 more source

MyD88 Deficiency Protects Mice From Experimental Autoimmune Encephalomyelitis by Influencing Both Dendritic Cells and T Cells

Immunology, EarlyView.
This study investigates the role of MyD88 in dendritic cells (DCs) and T cells during experimental autoimmune encephalomyelitis (EAE). We found that MyD88 is highly expressed in DCs and CD4+ T cells in people with multiple sclerosis, and its deficiency impairs DC maturation, reduces pro‐inflammatory cytokine production, weakens DC–T cell interactions ...
Wen Si, Gaochen Zhu, Qianling Jiang, Xin Ma, Guan Yang   +4 more
wiley   +1 more source

Temporal and regional dynamics of Mycobacterium tuberculosis in Oman. [PDF]

Sci Rep
Hashim RA, Al Zubaidi A, Al Ghafri F, Al-Jardani A, Al-Azri S, Yagoubi FA, Balkhair AA, Al Kindi A, Balushi LA, Al Zadjali S, Al-Hamidhi S, Gadalla AAH, Babiker A, Pérez-Pardal L, Beja-Pereira A, Babiker HA.   +15 more
europepmc   +1 more source

Insight into the PZA resistance whole genome of Mycobacterium tuberculosis isolates from Khyber Pakhtunkhwa, Pakistan [PDF]

, 2020
Muhammad Tahir Khan, Sajid Ali, Anwar Sheed Khan, Arif Ali, Abbas Khan, Aman Chandra Kaushak, Muhammad Irfan, Satheshkumar Chinnasamy, Shulin Zhang, Yu‐Juan Zhang, Zhelie Cui, Amie Jinghua Wei, Yanjie Wang, Mingzhu Zhao, Kejia Liu, Muhammad Tariq Zeb, Heng wang, Dong‐Qing Wei   +17 more
openalex   +1 more source

The Dual Immunoregulatory Role of CREB3L1 Underlying Latent and Severe Tuberculosis Clinical Manifestation

Immunology, EarlyView.
RNA‐seq of lungs and livers from Mycobacterium tuberculosis‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and ...
Felipe T. Lima, Ricardo C. Castro, Francisco R. Javier, Caroline Fontanari, Valdes R. Bollela, Rogerio S. Rosada, Célio L. Silva, Lúcia H. Faccioli, Luiz G. Gardinassi, Fabiani G. Frantz   +9 more
wiley   +1 more source

Photodynamic inactivation of Mycobacterium tuberculosis by broad-spectrum visible light. [PDF]

Appl Microbiol Biotechnol
D'Agostini C, Prezioso C, Checconi P, Camicia V, Pelliccioni M, Di Traglia L, Minieri M, Legramante JM, Garaci E, Limongi D.   +9 more
europepmc   +1 more source

Multiple bilateral costo–chondral abscesses due to Mycobacterium tuberculosis

, 2010
G Péter, SR Basti, AS Joy
openalex   +1 more source

Signal Transducer and Activator of Transcription (STAT) Proteins Regulate Mucosal‐Associated Invariant T (MAIT) Cell Function

Immunology, EarlyView.
Integrated transcriptomic, proteomic and flow cytometry analyses reveal that STAT1 negatively regulates MAIT cell effector and glycolytic functions, while STAT3, STAT5 and HIF1α act as positive modulators. Targeting these pathways may offer new strategies to restore MAIT cell function in immune dysregulation and cancer.
Olivia J. Cheng, Eimear K. Ryan, Michael Bennett, Christy Clutter, Jackson G. Cacioppo, Jeffrey Aubé, Andy E. Hogan, Daniel T. Leung   +7 more
wiley   +1 more source

Research progress on protein tyrosine phosphatase A from Mycobacterium tuberculosis. [PDF]

Front Immunol
Cai Y, Zhang L.
europepmc   +1 more source