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Trends in Microbiology, 2018
In this infographic, the genetics, phylogeny, physiology, and pathogenesis mechanisms of Mycobacterium tuberculosis are shown. Mycobacterium tuberculosis is the etiological agent of tuberculosis (TB), the leading cause of death due to a single infectious agent, claiming 1.7 million lives in 2016.
A. Koch, V. Mizrahi
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In this infographic, the genetics, phylogeny, physiology, and pathogenesis mechanisms of Mycobacterium tuberculosis are shown. Mycobacterium tuberculosis is the etiological agent of tuberculosis (TB), the leading cause of death due to a single infectious agent, claiming 1.7 million lives in 2016.
A. Koch, V. Mizrahi
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Revue des Maladies Respiratoires Actualités, 2020
P. Fraisse, M. Maillet, C. Janssen
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P. Fraisse, M. Maillet, C. Janssen
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On the sociology of Mycobacterium tuberculosis
Tuberculosis, 2014I think I have undervalued the role of horizontal transfer in shaping the genome of Mycobacterium tuberculosis. My excuse for this is that no plasmids have been isolated fromM. tuberculosis and that the phylogeny of the M. tuberculosis complex can be explained without invoking any substantive contribution from exogenous DNA. If M.
Douglas B. Young, Douglas B. Young
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Recombineering in Mycobacterium tuberculosis
Nature Methods, 2006Genetic dissection of M. tuberculosis is complicated by its slow growth and its high rate of illegitimate recombination relative to homologous DNA exchange. We report here the development of a facile allelic exchange system by identification and expression of mycobacteriophage-encoded recombination proteins, adapting a strategy developed previously for
Julia C. van Kessel, Graham F. Hatfull
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The scent of Mycobacterium tuberculosis
Tuberculosis, 2008Worldwide, tuberculosis (TB) kills nearly 2 million people annually, yet rapid diagnosis still relies on a 100-year-old method of sputum staining for acid-fast bacilli. The advent of solid phase micro-extraction and gas chromatography/mass spectrometry makes it possible to systematically investigate whether volatile metabolites from organisms belonging
Mona Syhre, Stephen T. Chambers
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Mycobacterium Tuberculosis Infection
, 2018Phagocytosis of tubercle bacilli by antigen-presenting cells in human lung alveoli initiates a complex infection process by Mycobacterium tuberculosis and a potentially protective immune response by the host. M.
MI Sahadulla
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Metabolomics of Mycobacterium tuberculosis [PDF]
, 2015 Enzymes fuel the biochemical activities of all cells. Their substrates and products thus offer a potential window into the physiologic state of a cell. Metabolomics focuses on the global, or systems-level, study of small molecules in a given biological system and thus provided an experimental tool with which to study cellular physiology on a global ...
Gareth A. Prosser +3 more
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Microarrays for Mycobacterium tuberculosis
Tuberculosis, 2004This special microarray issue of Tuberculosis recognises the important contributions of M. tuberculosis whole genome DNA microarrays to tuberculosis research by bringing together a range of papers that address M. tuberculosis physiology, host-pathogen interactions, mechanisms of drug action, in vitro and in vivo gene expression, host responses ...
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Osteoarticular Mycobacterium Tuberculosis
Orthopaedic Nursing, 1996Osteoarticular mycobacterium tuberculosis (TB) can present as a subtle insidious infection. Symptoms vary with bone TB. Osteoarticular TB generally responds to proper antimicrobial therapy, affording sufficient treatment and arrest of the disease process. Epidemiology, pathogenesis, treatment, and a case review are presented in this article.
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