Results 251 to 260 of about 382,621 (326)

Radiogenomics: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 2, February 2026.
Radiogenomics links imaging phenotypes with genetic variations, offering potential for comprehensive understanding, cost‐effective diagnosis, and prognosis prediction to advance personalized medicine. However, its clinical application remains limited by several challenges.
Xinyu Zhang, Qingpei Lai, Jin Cao, Jerry Chi Fung Ching, Xinzhi Teng, Jiang Zhang, Shara Wee Yee Lee, Ge Ren, Jing Cai   +8 more
wiley   +1 more source

Zinc pyrithione impairs iron-sulfur cluster biogenesis in Mycobacterium tuberculosis. [PDF]

BMC Microbiol
Wang L, Wang X, Xu L, Wang B, Ji D, Ye Y, Lu Y.   +6 more
europepmc   +1 more source

Modulation of succinyl‐CoA:3‐ketoacid CoA transferase activity by a single amino acid residue in acetate:succinate CoA transferase from Trypanosoma brucei, the causative agent of African sleeping sickness

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Trypanosomatids are protozoan parasites that remain a global health challenge due to the limited efficacy, safety, and durability of current treatments. Acetate: succinate CoA transferase (ASCT), together with succinyl‐CoA synthase (SCS), forms the ASCT/SCS cycle that fuels ATP production and generates acetate, a central metabolic intermediate
Kota Mochizuki, Daniel Ken Inaoka, Keisuke Fukuda, Hana Kurasawa, Kenji Iyoda, Uta Nakai, Shigeharu Harada, Emmanuel O. Balogun, Frédéric Bringaud, Michael Boshart, Takaya Sakura, Kenji Hirayama, Kiyoshi Kita, Tomoo Shiba   +13 more
wiley   +1 more source

Inhibition of de novo fatty acid synthesis in Mycobacterium tuberculosis. [PDF]

J Biol Chem
Roszkowski EK, Charap S, Montague CR, Sukheja P, McNamara CW, Soma PS, Islam MN, Graham B, Grzegorzewicz AE, Jackson M, Yang B, Hay AG, Russell DG, Belisle JT, VanderVen BC.   +14 more
europepmc   +1 more source

Faculty Opinions recommendation of Rapid and simple approach for identification of Mycobacterium tuberculosis complex isolates by PCR-based genomic deletion analysis.

, 2002
Gaby E. Pfyffer
openalex   +2 more sources

Diversity of FAAL enzymes and prediction of their substrate specificity using FAALPred

Protein Science, Volume 35, Issue 2, February 2026.
Abstract FAALs (fatty acyl‐AMP ligases) recruit and incorporate fatty acids during the biosynthesis of secondary metabolites. Their diversity, distribution, and substrate specificity remain poorly understood, which limits functional predictions from sequence data.
Anne Liong, Leandro de Mattos Pereira, Pedro N. Leão   +2 more
wiley   +1 more source

A co-evolutionary perspective on humans and <i>Mycobacterium tuberculosis</i> in the era of systems biology. [PDF]

Elife
Reichmann MT, Tezera LB, Denney L, Schiff H, Vallejo A, Mansour S, Leslie A, Garay-Baquero DJ, Elkington PT.   +8 more
europepmc   +1 more source

TNF Inhibitor‐Induced Sarcoidosis‐Like Lesions in Inflammatory Bowel Disease

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background While tumor necrosis factor (TNF) inhibitors can induce paradoxical reactions, sarcoidosis‐like disease has hardly been reported so far. This study aimed to describe the epidemiological, diagnostic and therapeutic features of TNF inhibitor‐induced sarcoidosis‐like lesions in patients with inflammatory bowel disease.
Zlata Chkolnaia, Benedicte Lebrun‐Vignes, Aurelien Amiot, Mathieu Uzzan, Nicolas Richard, Maeva Charkaoui, Guillaume Le Cosquer, Carmen Stefanescu, Melanie Serrero, Laurianne Plastaras, Sophie Vieujean, David Laharie, Philippe Seksik   +12 more
wiley   +1 more source

Genomic epidemiology of Mycobacterium tuberculosis in Wales. [PDF]

Sci Rep
Pacchiarini N, Simkin F, Postans M, Ahern G, Song J, Brown C, Smith J, Williams C, Backx M, Thomas D, Connor TR, Williams C.   +11 more
europepmc   +1 more source