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The transcriptome of Mycobacterium tuberculosis

Applied Microbiology and Biotechnology, 2010
In this review, we summarize the present understanding of the Mycobacterium tuberculosis transcriptome and catalog both experimentally verified findings and computationally derived predictions. We also provide a new analysis for a range of discoveries by comparing the results of previously independent research papers.
Rachel Haller   +3 more
openaire   +3 more sources

Metabolomics of Mycobacterium tuberculosis

2021
Enzymes fuel the biochemical activities of all cells. Their substrates and products thus represent a potential window into the physiologic state of a cell. Metabolomics focuses on the global, or systems-level, study of small molecules in a given biological system and has thus provided an experimental tool with which to study cellular physiology ...
Kyle A, Planck, Kyu, Rhee
openaire   +2 more sources

Latent Mycobacterium tuberculosis infection.

New England Journal of Medicine, 2015
The natural history of tuberculosis begins with the inhalation of Mycobacterium tuberculosis organisms; a period of bacterial replication and dissemination ensues, followed by immunologic containment of viable bacilli.
H. Getahun   +3 more
semanticscholar   +1 more source

Mycobacterium tuberculosis – The Organism

2008
The question of whether tuberculosis was due to a transmissible agent or to an inherited disposition was a subject of controversy in the nineteenth century, but the 1868 demonstration by Jean Antoine Villemin that inoculation of tuberculous material from humans and cattle into rabbits elicited characteristic granulomatous lesions swung the argument ...
openaire   +2 more sources

Evolution of Mycobacterium tuberculosis

2013
Genomic studies have provided a refined understanding of the genetic diversity within the Mycobacterium genus, and more specifically within Mycobacterium tuberculosis. These results have informed a new perspective on the macro- and micro-evolution of the tubercle bacillus. In the first step, a M. kansasii-like opportunistic pathogen acquired new genes,
openaire   +3 more sources

Mycobacterium tuberculosis

2002
Publisher Summary Mycobacterium tuberculosis is the causative agent of tuberculosis (TB). Recent years have seen the resurgence of TB, particularly where there is a high prevalence of human immunodeficiency virus (HIV) infection. Most mycobacteria are saprophytes in soil or water and are harmless to humans; however, at some point thousands of years ...
Howard N. Cooper   +2 more
openaire   +2 more sources

Enhancing global access to cancer medicines

Ca-A Cancer Journal for Clinicians, 2020
Javier Cortés   +2 more
exaly  

Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis

Nature Genetics, 2018
Francesc Coll   +50 more
semanticscholar   +1 more source

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