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The transcriptome of Mycobacterium tuberculosis
Applied Microbiology and Biotechnology, 2010In this review, we summarize the present understanding of the Mycobacterium tuberculosis transcriptome and catalog both experimentally verified findings and computationally derived predictions. We also provide a new analysis for a range of discoveries by comparing the results of previously independent research papers.
Rachel Haller+3 more
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Metabolomics of Mycobacterium tuberculosis
2021Enzymes fuel the biochemical activities of all cells. Their substrates and products thus represent a potential window into the physiologic state of a cell. Metabolomics focuses on the global, or systems-level, study of small molecules in a given biological system and has thus provided an experimental tool with which to study cellular physiology ...
Kyle A, Planck, Kyu, Rhee
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Latent Mycobacterium tuberculosis infection.
New England Journal of Medicine, 2015The natural history of tuberculosis begins with the inhalation of Mycobacterium tuberculosis organisms; a period of bacterial replication and dissemination ensues, followed by immunologic containment of viable bacilli.
H. Getahun+3 more
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Mycobacterium tuberculosis – The Organism
2008The question of whether tuberculosis was due to a transmissible agent or to an inherited disposition was a subject of controversy in the nineteenth century, but the 1868 demonstration by Jean Antoine Villemin that inoculation of tuberculous material from humans and cattle into rabbits elicited characteristic granulomatous lesions swung the argument ...
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Evolution of Mycobacterium tuberculosis
2013Genomic studies have provided a refined understanding of the genetic diversity within the Mycobacterium genus, and more specifically within Mycobacterium tuberculosis. These results have informed a new perspective on the macro- and micro-evolution of the tubercle bacillus. In the first step, a M. kansasii-like opportunistic pathogen acquired new genes,
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2002
Publisher Summary Mycobacterium tuberculosis is the causative agent of tuberculosis (TB). Recent years have seen the resurgence of TB, particularly where there is a high prevalence of human immunodeficiency virus (HIV) infection. Most mycobacteria are saprophytes in soil or water and are harmless to humans; however, at some point thousands of years ...
Howard N. Cooper+2 more
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Publisher Summary Mycobacterium tuberculosis is the causative agent of tuberculosis (TB). Recent years have seen the resurgence of TB, particularly where there is a high prevalence of human immunodeficiency virus (HIV) infection. Most mycobacteria are saprophytes in soil or water and are harmless to humans; however, at some point thousands of years ...
Howard N. Cooper+2 more
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Ecology and evolution of Mycobacterium tuberculosis
Nature Reviews Microbiology, 2018S. Gagneux
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Enhancing global access to cancer medicines
Ca-A Cancer Journal for Clinicians, 2020Javier Cortés+2 more
exaly
Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis
Nature Genetics, 2018Francesc Coll+50 more
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