Results 51 to 60 of about 833,621 (293)

Assessing the accuracy of the updated Fujifilm SILVAMP TB LAM II assay between lot numbers

open access: yesIJTLD Open
BACKGROUND: The Fujifilm SILVAMP TB LAM (FujiLAM) assay, a point-of-care test detecting urine-based lipoarabinomannans, has demonstrated notable diagnostic accuracy for TB. However, FujiLAM exhibits lot-to-lot variability, limiting its clinical use.
K. Chikamatsu   +3 more
doaj   +1 more source

Aktivitas Anti Mycobacterium tuberculosis Strain H37Rv dan MDR (Multi Drug Resistant) dari Ekstrak Rimpang Curcuma mangga Val.

open access: yesJurnal Farmasi Galenika (Galenika Journal of Pharmacy), 2020
TB is an infectious disease caused by the bacterium Mycobacterium tuberculosis. Empirically the plants that have long been used in medicine are Curcuma mangga  rhizome, which shows pharmacological activity as an anti Mycobacterium tuberculosis drug.
Ritha Pratiwi   +3 more
doaj   +1 more source

The New Xpert MTB/RIF Ultra: Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testing

open access: yesmBio, 2017
The Xpert MTB/RIF assay (Xpert) is a rapid test for tuberculosis (TB) and rifampin resistance (RIF-R) suitable for point-of-care testing. However, it has decreased sensitivity in smear-negative sputum, and false identification of RIF-R occasionally ...
S. Chakravorty   +24 more
semanticscholar   +1 more source

Microevolution ofMycobacterium tuberculosisin a Tuberculosis Patient [PDF]

open access: yesJournal of Clinical Microbiology, 2010
ABSTRACTFiveMycobacterium tuberculosisisolates were obtained from three body sites from a Dutch patient. The isolates displayed a single genotype by 24-locus MIRU-VNTR typing (except for a single locus not amplified from one isolate) but were differentiated by small variations in IS6110fingerprints, spoligotypes, 6 hypervariable MIRU-VNTR loci, and/or ...
Al-Hajoj, SAM   +8 more
openaire   +5 more sources

Molecular epidemiology of Mycobacterium africanum in Ghana [PDF]

open access: yes, 2016
BACKGROUND: Mycobacterium africanum comprises two phylogenetic lineages within the M. tuberculosis complex (MTBC) and is an important cause of human tuberculosis (TB) in West Africa. The reasons for this geographic restriction of M.
Ahorlu, Collins   +13 more
core   +2 more sources

IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure

open access: yesNature Network Boston, 2019
Exposure to Mycobacterium tuberculosis (Mtb) results in heterogeneous clinical outcomes including primary progressive tuberculosis and latent Mtb infection (LTBI).
Lenette L. Lu   +20 more
semanticscholar   +1 more source

ACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteria [PDF]

open access: yes, 2009
Mycolic acids are essential for the survival, virulence and antibiotic resistance of the human pathogen Mycobacterium tuberculosis. Inhibitors of mycolic acid biosynthesis, such as isoniazid and ethionamide, have been used as efficient drugs for the ...
Bazet Lyonnet, Bernardo   +7 more
core   +2 more sources

Mycobacterium tuberculosis is less likely to acquire pathogenic mutations during latent infection than during active disease

open access: yesMicrobiology Spectrum
Most people infected with Mycobacterium tuberculosis (Mtb) are believed to be in a state of latent tuberculosis (TB) infection (LTBI). Although LTBI is asymptomatic and not infectious, there is a risk of developing active disease even decades after ...
Asami Osugi   +5 more
doaj   +1 more source

DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]

open access: yes, 2010
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams   +117 more
core   +1 more source

Mycobacterium tuberculosis monoarthritis in a child [PDF]

open access: yesPediatric Rheumatology, 2008
A child with isolated Mycobacterium tuberculosis monoarthritis, with features initially suggesting oligoarthritis subtype of juvenile idiopathic arthritis, is presented. This patient illustrates the need to consider the possibility of tuberculosis as the cause of oligoarthritis in high-risk pediatric populations even in the absence of a tuberculosis ...
Alan M. Rosenberg, Derek Rajakumar
openaire   +4 more sources

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