Results 51 to 60 of about 5,659 (219)
This educational video explains the crucial operative steps in completing a transaortic septal myectomy for the treatment of hypertrophic obstructive cardiomyopathy.
Pietro Bajona (6420551) +1 more
core +1 more source
Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers +5 more
wiley +1 more source
Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska +6 more
wiley +1 more source
Septal 3D Anatomy to Guide a Septal Myectomy
This video describes the authors’ surgical technique to treat severe symptomatic hypertrophic obstructive cardiomyopathy through a median sternotomy. This technique is mainly inspired from the Morrow septal myectomy.
Nicholas Smerida (12316967)
core +1 more source
Hypertrophic cardiomyopathy is a heart muscle disease with an annual incidence between 0.24 and 0.47/100000 in childhood. Sudden cardiac death is the most common cause of death in this population.
Paola Dolader +6 more
doaj +1 more source
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato +3 more
wiley +1 more source
Background Myectomy remains the standard surgical treatment of patients with hypertrophic cardiomyopathy (HOCM). New surgical methods developed in the last decades mainly address the mitral valve and are controversial because of their conflicting ...
Mateusz Kuć +6 more
doaj +1 more source
ABSTRACT Background and Aim Emerging endoscopic techniques are expanding opportunities for minimally invasive therapy in early colorectal cancers (CRCs). Data regarding the clinicopathological features and outcomes of colon versus rectal cancers in Tis, T1, and T2 stages remain limited.
Shunto Iwasaki +17 more
wiley +1 more source
Success and limitations of right ventricular sinus myectomy for pulmonary atresia with intact ventricular septum [PDF]
ObjectivesRight ventricular sinus myectomy has been proposed for pulmonary atresia with intact ventricular septum for morphology falling within the uncertain area for eventual biventricular repair.
Mohan, Uthara +17 more
core +1 more source
Introduction and ObjectivesThe risk of ventricular arrhythmia and heart failure in patients with hypertrophic obstructive cardiomyopathy (HOCM) is much higher than that in the general population.
Jilin Zheng (4029908) +8 more
core +1 more source

