Results 61 to 70 of about 5,900 (221)

Current state of the art and future of myectomy [PDF]

Annals of Cardiothoracic Surgery, 2017
Surgical relief of left ventricular outflow tract obstruction (LVOTO) in hypertrophic cardiomyopathy (HCM) requires more than septal myectomy. The procedure is currently the gold standard for all symptomatic HCM patients except those with comorbidities. The operation requires an individualized approach to restore the sophisticated functions of the left
Magdi H, Yacoub, Ahmed, Afifi, Hesham, Saad, Heba, Aguib, Ahmed, ElGuindy   +4 more
openaire   +2 more sources

Adverse Pathological Features and Worse Prognosis in Rectal Cancer Compared With Colon Cancer in T1 and T2 Stages

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background and Aim Emerging endoscopic techniques are expanding opportunities for minimally invasive therapy in early colorectal cancers (CRCs). Data regarding the clinicopathological features and outcomes of colon versus rectal cancers in Tis, T1, and T2 stages remain limited.
Shunto Iwasaki, Shin‐ei Kudo, Yuta Kouyama, Katsuro Ichimasa, Shigenori Semba, Yuriko Morita, Yuki Takashina, Tomotaka Takizawa, Yu Nimura, Taishi Okumura, Kenta Nakahara, Yasuharu Maeda, Noriyuki Ogata, Takemasa Hayashi, Naruhiko Sawada, Toshiyuki Baba, Tetsuo Nemoto, Masashi Misawa   +17 more
wiley   +1 more source

Myectomy for Giant Zenker’s Diverticulum

Turkish Journal of Gastroenterology
Cite this article as: Abayli B, Simsek Y, Ozer AI, Kuvvetli A, Avci BS, Avci A. Myectomy for giant Zenker’s diverticulum. Turk J Gastroenterol. Published online November 21, 2025. doi:10.5152/tjg.2025.25503.
Bahri Abayli, Yeliz Simsek, Ali Ilker Ozer, Adnan Kuvvetli, Begum Seyda Avci, Akkan Avci   +5 more
openaire   +2 more sources

Septal myectomy remains the gold standard [PDF]

European Heart Journal, 2012
This editorial refers to ‘A contemporary European experience with surgical septal myectomy in hypertrophic cardiomyopathy’, by A. Iacovoni et al. , doi:10.1093/eurheartj/ehs064 Improvements in the understanding of the haemodynamic abnormalities and pathophysiology of obstructive hypertrophic cardiomyopathy (HCM), as well as advances in surgical ...
openaire   +2 more sources

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

Movement Disorders, Volume 41, Issue 10, Page 2564-2591, October 2026.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska, Maresa Buchholz, Audrey Iskandar, Marcus Grobe‐Einsler, Thomas Klockgether, Jennifer Faber, Bernhard Michalowsky   +6 more
wiley   +1 more source

Long-term outcomes of surgery for obstructive hypertrophic cardiomyopathy in a pediatric cohortCentral MessagePerspective

JTCVS Open, 2023
Background: Septal reduction therapy via septal myectomy or a modified Konno procedure is the mainstay of therapy for drug-refractory obstructive hypertrophic cardiomyopathy (HCM), although outcomes data on septal myectomy in pediatric patients are ...
Stephanie N. Nguyen, MD, Megan M. Chung, BA, Alice V. Vinogradsky, BA, Marc E. Richmond, MD, MS, Warren A. Zuckerman, MD, Andrew B. Goldstone, MD, PhD, Emile A. Bacha, MD   +6 more
doaj   +1 more source

Pharmacological Inhibition of Small Extracellular Vesicle Secretion by ALK5i SD‐208 via Lysosomal Rerouting of CD63+ Compartments

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Pharmacological tools to selectively modulate extracellular vesicle (EV) secretion are scarce. Here, we identify the ALK5 (TGF‐β receptor I) inhibitor SD‐208 as a potent suppressor of small EV (sEV) secretion that acts independently of its canonical anti‐fibrotic activity.
Rahul Sanwlani, Georgina H. Thompson, Kyle Bramich, Ching‐Seng Ang, Millie L. Trowbridge, Chris E. Duringer, Vlad Stolojan, Sean M. Davidson, Konstantinos Savvatis, John H. McVey, Suresh Mathivanan, Aled Clayton, Patrizia Camelliti   +12 more
wiley   +1 more source

Transaortic septal myectomy: techniques and pitfalls [PDF]

ASVIDE, 2017
Hypertrophic cardiomyopathy (HCM) is the most common congenital cardiac disease, affecting up to 1 in 200 individuals. When it causes left ventricular outflow tract (LVOT) obstruction, treatment is indicated to reduce symptoms and the risk of sudden cardiac death. Pharmacologic therapy is the first line treatment, however if it fails, surgical myectomy
Anthony, Ralph-Edwards, Rachel D, Vanderlaan, Pietro, Bajona   +2 more
openaire   +2 more sources

Infective Endocarditis Diagnosed by Emergency Physicians Using Cardiac POCUS: A Case Series

Australasian Journal of Ultrasound in Medicine, Volume 29, Issue 3, August 2026.
ABSTRACT Introduction Emergency physicians (EPs) are acquiring ever‐increasing expertise in cardiac point‐of‐care ultrasound (POCUS). We compiled this case series to demonstrate current practice by EPs diagnosing infective endocarditis (IE) using POCUS.
Jonathan Henry, Mark Rugless, Claudiu Radeanu, Abrar Waliuddin, Kevin Phang, Allan Whitehead, Shanu Khader, David Henry, Darsim Haji   +8 more
wiley   +1 more source

Surgical myectomy: Rationale and personalized technique

Global Cardiology Science and Practice, 2018
Septal myectomy is currently the gold standard treatment for symptomatic patients with hypertrophic cardiomyopathy. The procedure needs to be tailored and performed in a personalized fashion, taking into consideration the anatomical spectrum of this disease.The procedure needs to address the various components that contribute to the clinical and ...
Hamood Al Kindi, Magdi H. Yacoub
openaire   +3 more sources