Results 91 to 100 of about 184,937 (258)

Bilateral optic neuritis as a presentation of myelin oligodendrocyte glycoprotein antibody associated disease in a child

open access: yesIndian Journal of Ophthalmology. Case Reports, 2023
Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), although rare, is now recognized as a distinct demyelinating disorder. The entity differs from multiple sclerosis and neuromyelitis optica spectrum disorder in terms of clinical ...
Sai Lakshmi Raghavan   +3 more
doaj   +1 more source

Serum biomarkers in myelin oligodendrocyte glycoprotein antibody–associated disease

open access: yesNeurology: Neuroimmunology & Neuroinflammation, 2020
Objective To test the hypothesis that the pattern of serum biomarkers of disease activity and disability in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) will be different from those in neuromyelitis optica spectrum disorder ...
Hyunjin Kim   +7 more
semanticscholar   +1 more source

Comparative Analysis of Choroid Plexus Volume Between MOG Antibody Associated Disease and Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Choroid plexus volume (CPV) has been proposed as a neuro‐immunological marker of multiple sclerosis (MS), but its relevance in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) remains uncertain. We analyzed CPV in 43 individuals with MOGAD, 48 with MS, and 44 healthy controls using a Bayesian Gaussian mixture modeling ...
Jae‐Won Hyun   +4 more
wiley   +1 more source

Structure and Polymorphism of the Mouse Myelin/Oligodendrocyte Glycoprotein Gene

open access: yesGenomics, 1994
We have isolated and characterized genomic clones containing the mouse myelin/oligodendrocyte glycoprotein (MOG) gene. It spans a region of 12.5 kb and consists of eight exons. Its exon-intron structure differs from that of classical MHC-class I genes, with which it is linked in the mouse genome.
P, Daubas, D, Pham-Dinh, A, Dautigny
openaire   +2 more sources

“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez   +29 more
wiley   +1 more source

Antibodies to myelin oligodendrocyte glycoprotein in idiopathic optic neuritis [PDF]

open access: yesBMJ Open, 2015
ObjectivesTo investigate the differences of clinical features, cerebrospinal fluid (CSF), MRI findings and response to steroid therapies between patients with optic neuritis (ON) who have myelin oligodendrocyte glycoprotein (MOG) antibodies and those who have seronegative ON.SettingWe recruited participants in the department of neurology and ...
Nakajima, Hideki   +12 more
openaire   +2 more sources

Overlapping demyelinating syndrome and anti-N-methyl-d-aspartate receptor encephalitis with seizures

open access: yesEpilepsy & Behavior Reports, 2019
Anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis, the most recognized type of autoimmune encephalitis, manifests with rapid cognitive decline, psychosis, and seizures that develop in 78–86% of patients.
Olga Taraschenko, Rana Zabad
doaj   +1 more source

Serial Anti–Myelin Oligodendrocyte Glycoprotein Antibody Analyses and Outcomes in Children With Demyelinating Syndromes

open access: yesJAMA Neurology, 2019
Key Points Question Are antibodies to myelin oligodendrocyte glycoprotein (MOG) associated with relapses in children with acquired demyelination?
P. Waters   +13 more
semanticscholar   +1 more source

Myelin oligodendrocyte glycoprotein (MOG) antibody-mediated disease: The difficulty of predicting relapses

open access: yesMultiple Sclerosis and Related Disorders, 2021
Background: While many patients with myelin oligodendrocyte glycoprotein antibody-mediated disease (MOG-AD) will have a monophasic course, 30-80% of patients will relapse after the initial attack. It is not known which factors predict relapse.
Samantha Epstein   +15 more
semanticscholar   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab   +19 more
wiley   +1 more source

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