Results 211 to 220 of about 184,937 (258)
Amaurosis Fugax Dolorosa: A Prodromal Syndrome in Optic Neuritis Associated With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. [PDF]
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Myelin Oligodendrocyte Glycoprotein Antibody-Associated Cerebral Cortical Encephalitis: A Comparative Study With Antibody-Negative and Non-MOG Antibody-Positive Cortical Encephalitis in Chinese Adults. [PDF]
Yin Q +7 more
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Autoantibodies to myelin oligodendrocyte glycoprotein in pediatric MS
McLaughlin, Katherine A. +14 more
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Myelin Oligodendrocyte Glycoprotein and Multiple Sclerosis
Medicinal Chemistry, 2018Myelin oligodendrocyte glycoprotein (MOG) is located on the external surface of myelin, a membranous component of the central nervous system (CNS) that forms the insulating lipid layer around neurons. The major MOG splicing variant (a1 transcript) encodes a transmembrane protein with an extracellular domain of an Ig variable (IgV) fold. MOG IgV domains
Theodore Tselios +1 more
exaly +3 more sources
Myelin oligodendrocyte glycoprotein antibodies in neurological disease
Nature Reviews Neurology, 2018Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies (MOG-Abs) were first detected by immunoblot and enzyme-linked immunosorbent assay nearly 30 years ago, but their association with multiple sclerosis (MS) was not specific. Use of cell-based assays with native MOG as the substrate enabled identification of a group of MOG-Ab-positive patients with
M. Reindl, P. Waters
semanticscholar +3 more sources
Optic perineuritis with anti-myelin oligodendrocyte glycoprotein antibody
Multiple Sclerosis and Related Disorders, 2020A 25-year-old male presented with blurred peripheral vision and movement pain in his right eye. Fundus examination revealed unilateral disc swelling in his right eye with normal intracranial pressure. MRI showed remarkably high intensity in the optic nerve sheath and slightly high intensity in the optic nerve, indicating optic perineuritis (OPN).
Takaaki Hattori +2 more
exaly +3 more sources
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease.
ContinuumOBJECTIVE This article reviews the clinical features, MRI attributes, serologic aspects, diagnostic criteria, treatment, and prognosis of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).
E. Flanagan, Cheryl Hemingway
semanticscholar +2 more sources
European Journal of Neurology, 2023
The kappa free light chains index (κ‐index) is increasing in importance as a fast, easy, cost‐effective, and quantitative biomarker in multiple sclerosis (MS), which can replace cerebrospinal fluid (CSF)‐restricted oligoclonal bands (OCB) detection.
R. Deschamps +11 more
semanticscholar +1 more source
The kappa free light chains index (κ‐index) is increasing in importance as a fast, easy, cost‐effective, and quantitative biomarker in multiple sclerosis (MS), which can replace cerebrospinal fluid (CSF)‐restricted oligoclonal bands (OCB) detection.
R. Deschamps +11 more
semanticscholar +1 more source
Pediatric Neurology, 2023
BACKGROUND We describe a cohort of children with severe myelin oligodendrocyte glycoprotein (MOG)-IgG-associated cerebral cortical encephalitis (CCE), manifesting with bilateral cortical cytotoxic edema and critical neurological illness.
V. Kannan +12 more
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BACKGROUND We describe a cohort of children with severe myelin oligodendrocyte glycoprotein (MOG)-IgG-associated cerebral cortical encephalitis (CCE), manifesting with bilateral cortical cytotoxic edema and critical neurological illness.
V. Kannan +12 more
semanticscholar +1 more source

