Results 221 to 230 of about 184,937 (258)

Membrane topology of the myelin/oligodendrocyte glycoprotein

European Journal of Biochemistry, 1998
Myelin/oligodendrocyte glycoprotein (MOG), a specific component of the mammalian central nervous system, is located on the surface of the oligodendrocyte plasma membrane and the outermost lamellae of mature myelin; it is expressed during the latter steps of myelinogenesis.
B, della Gaspera, D, Pham-Dinh, G, Roussel, J L, Nussbaum, A, Dautigny   +4 more
openaire   +2 more sources

Myelin oligodendrocyte glycoprotein (MOG) polymorphisms and adrenoleukodystrophy

Journal of Neuroimmunology, 2000
We describe four novel sequence variants in the Myelin Oligodendrocyte Glycoprotein (MOG) gene. A total of six sequence variants of the MOG gene were identified in eleven out of 44 ALD patients investigated: G15A, CTC repeat in exon 1, Val142Leu, Val145Ile, 551+68A-->G and 551+77C-->T.
M, Gomez-Lira, M G, Marzari, G, Uziel, P, Pignatti, N, Rizzuto, A, Salviati   +5 more
openaire   +2 more sources

Myelin oligodendrocyte glycoprotein antibody-associated disease: an immunopathological study.

Brain : a journal of neurology, 2020
Conformation-sensitive antibodies against myelin oligodendrocyte glycoprotein (MOG) are detectable in patients with optic neuritis, myelitis, opticomyelitis, acute or multiphasic disseminated encephalomyelitis (ADEM/MDEM) and brainstem/cerebral cortical ...
Y. Takai, T. Misu, K. Kaneko, N. Chihara, K. Narikawa, S. Tsuchida, Hiroya Nishida, T. Komori, Morinobu Seki, Teppei Komatsu, K. Nakamagoe, Toshimasa Ikeda, Mari Yoshida, Toshiyuki Takahashi, Hirohiko Ono, Shuhei Nishiyama, H. Kuroda, I. Nakashima, Hiroyoshi Suzuki, M. Bradl, H. Lassmann, K. Fujihara, M. Aoki, Y. Otsuka, K. Nishimaki, Sho Ishigaki, Kazunari Yoshida, Yasuyuki Iguchi, T. Fukuda, Seitaro Nohara, Akira Tamaoka, J. Fujimori   +31 more
semanticscholar   +1 more source

Associations of paediatric demyelinating and encephalitic syndromes with myelin oligodendrocyte glycoprotein antibodies: a multicentre observational study.

Lancet Neurology, 2020
BACKGROUND Investigations of myelin oligodendrocyte glycoprotein (MOG) antibodies are usually focused on demyelinating syndromes, but the entire spectrum of MOG antibody-associated syndromes in children is unknown.
T. Armangué, G. Olivé-Cirera, E. Martínez-Hernandez, M. Sepúlveda, Raquel Ruiz-García, M. Muñoz-Batista, H. Ariño, V. González-Álvarez, A. Felipe-Rucián, M. Martínez-González, V. Cantarín-Extremera, M. C. Miranda-Herrero, L. Monge-Galindo, M. Tomás-Vila, E. Miravet, Ignacio Málaga, G. Arrambide, C. Auger, M. Tintoré, X. Montalban, A. Vanderver, F. Graus, A. Saiz, J. Dalmau, Alberto Alcantud, S. Aguilera-Albesa, Diana Alvarez Demanuel, M. A. Molinero, L. Fariña, Luisa Arrabal, G. Arriola-Pereda, G. Aznar-Laín, Maite Benavides-Medina, Teresa Bermejo, R. Blanco-Lago, E. Caballero, Rocío Calvo, A. C. Salas, D. Conejo-Moreno, V. Delgadillo-Chilavert, Amagoia Elosegi-Castellanos, V. E. Canto, J. Fernández-Ramos, Montserrat Garcia-Puig, A. García-Ribes, H. Gómez-Martín, Desire Gonzalez-Barrios, L. González-Gutiérrez-Solana, Sara Jimena-García, M. Jiménez-Legido, N. Juliá-Palacios, E. López‐Laso, I. Martí-Carrera, Marta Martínez González, L. Martín-Viota, Simone Mattozi, Elena Maqueda-Castellote, M. Mendibe, M. D. Mora-Ramírez, B. Muñoz-Cabello, Juan Navarro-Morón, Tania Nunes-Cabrera, Gabriela Orellana, Berta Pujol-Soler, L. Querol, A. Ramírez, M. I. Rodriguez-Lucenilla, C. Ruiz, V. Soto-Insuga, L. Laguna, E. Turón-Viñas, M. Vázquez-López, Cristina Villar-Vera   +72 more
semanticscholar   +1 more source

Myelin/Oligodendrocyte Glycoprotein

1997
Myelinogenesis is an essential, highly regulated event that occurs during early mam-malian development whereby internodal axonal segments are enveloped by compacted multilamellar membranes. A single oligodendrocyte in the central nervous system (CNS) has the capacity to extend numerous processes, which develop into elaborate specialized membranes that ...
Minnetta V. Gardinier, Pauline A. Ballenthin, John F. Kroepfl, Laura R. Viise   +3 more
openaire   +1 more source

Predictors of a relapsing course in myelin oligodendrocyte glycoprotein antibody-associated disease

Journal of Neurology Neurosurgery & Psychiatry
Background Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a recently described demyelinating disorder, and children represent about 50% of all cases.
Akash Virupakshaiah, V. Schoeps, J. Race, M. Waltz, Siefaddeen Sharayahn, Zahra Nasr, Carson E. Moseley, Scott S. Zamvil, C. Gaudioso, Allison Schuette, T. Casper, John Rose, E. Flanagan, Moses Rodriguez, J. Tillema, T. Chitnis, M. Gorman, Jennifer Graves, L. Benson, M. Rensel, Aaron Abrams, L. Krupp, T. Lotze, G. Aaen, Y. Wheeler, T. Schreiner, A. Waldman, Janet Chong, S. Mar, Emmanuelle Waubant   +29 more
semanticscholar   +1 more source

Myelin oligodendrocyte glycoprotein polymorphisms and multiple sclerosis

Journal of Neuroimmunology, 2002
A detailed analysis of the coding sequences of myelin oligodendrocyte glycoprotei (MOG) gene was performed in multiple sclerosis (MS) patients and in control individuals and three new polymorphisms are described: T636C, nt 571+77C-->T (IVS 4), and nt 710-44A-->G (IVS 6).
GOMEZ, Maria Macarena, Moretto, G., Bonamini, D., BENEDETTI, MARIADONATA, PIGNATTI, Pierfranco, RIZZUTO, Nicolo', SALVIATI, Alessandro   +6 more
openaire   +2 more sources

Investigation of Myelin/Oligodendrocyte Glycoprotein Membrane Topology

Journal of Neurochemistry, 1996
Abstract: Myelin/oligodendrocyte glycoprotein (MOG) is a CNS‐specific integral membrane protein that is an atypical member of the immunoglobulin (Ig) superfamily with two potential transmembrane domains based upon hydropathy analysis. With only one other exception, all Ig family members possess a single or no membrane spanning region.
J F, Kroepfl, L R, Viise, A J, Charron, C, Linington, M V, Gardinier   +4 more
openaire   +2 more sources

Myelin oligodendrocyte glycoprotein immunoglobulin G-associated encephalomyelitis

Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2020
The article discusses the role of myelin oligodendrocyte glycoprotein immunoglobulin G (MOG-IgG) in demyelinating diseases of the central nervous system. Clinical phenotypes of demyelinating syndromes associated with MOG-IgG that are currently included into neuromyelitis optica spectrum disorders (NMOSD) are described.
D D, Eliseeva, A V, Vasiliev, A A, Shabalina, T O, Simaniv, M N, Zakharova   +4 more
openaire   +2 more sources

Myelin oligodendrocyte glycoprotein-IgG-associated optic neuritis

Current Opinion in Ophthalmology, 2018
Myelin oligodendrocyte glycoprotein (MOG)-IgG-associated optic neuritis has been established as a new entity of optic neuropathy. We will review recent advances in pathophysiology, diagnosis, and clinical manifestations of MOG-IgG-associated optic neuritis to better understand its distinctive characteristics.MOG is expressed on the surface of myelin ...
Bo Young, Chun, Dean M, Cestari
openaire   +2 more sources