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Myelin/oligodendrocyte glycoprotein is alternatively spliced in humans but not mice

Journal of Neuroscience Research, 1996
Myelin/oligodendrocyte glycoprotein (MOG) is an integral membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, MOG is a primary target antigen involved in immune-mediated demyelination.
P A, Ballenthin, M V, Gardinier
openaire   +2 more sources

Myelin/oligodendrocyte glycoprotein is a unique member of the immunoglobulin superfamily

Journal of Neuroscience Research, 1992
AbstractMyelin/oligodendrocyte glycoprotein (MOG) is a primary target autoantigen in experimental autoimmune encephalomyelitis, a widely used animal model for autoimmune demyelinating diseases such as multiple sclerosis. We have isolated several rat MOG cDNAs and confirmed their identity by comparision with MOG N‐terminal peptide sequence. As expected,
Gardinier MV   +3 more
openaire   +3 more sources

Comparison of the Response to Rituximab between Myelin Oligodendrocyte Glycoprotein and Aquaporin‐4 Antibody Diseases

Annals of Neurology, 2019
To compare response to rituximab (RTX) between adult patients positive for myelin oligodendrocyte glycoprotein (MOG) and aquaporin‐4 (AQP4) antibodies.
Pierre Durozard   +10 more
semanticscholar   +1 more source

Clinical phenotype, radiological features, and treatment of myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG) optic neuritis.

Current Opinion in Neurology, 2019
PURPOSE OF REVIEW To review the clinical characteristics, radiological manifestations and treatment of myelin oligodendrocyte glycoprotein (MOG)-immunoglobulin G (IgG) optic neuritis. RECENT FINDINGS Serum antibodies to MOG (MOG-IgG) have recently been
John J. Chen, M. Bhatti
semanticscholar   +1 more source

Relevance of antibodies to myelin oligodendrocyte glycoprotein in CSF of seronegative cases

Neurology, 2019
Objective To determine the diagnostic relevance of myelin oligodendrocyte glycoprotein antibodies (MOG-Abs) in CSF of seronegative cases by retrospectively analyzing consecutive time-matched CSF of 80 MOG-Ab–seronegative patients with demyelinating ...
S. Mariotto   +13 more
semanticscholar   +1 more source

Clinical characteristics of patients with myelin oligodendrocyte glycoprotein antibodies

Current Opinion in Neurology
Purpose of review The clinical landscape associated to myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) has undergone a remarkable transformation over the past two decades, primarily driven by advancements in antibody detection techniques that have enhanced both the specificity and sensitivity of assays, enabling the ...
Elisabeth, Maillart   +2 more
openaire   +2 more sources

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: Current Insights into the Disease Pathophysiology, Diagnosis and Management

International Journal of Molecular Sciences, 2021
Alicja Kalinowska-Lyszczarz   +2 more
exaly  

[Myelin Oligodendrocyte Glycoprotein Antibody Associated Disorders].

Brain and nerve = Shinkei kenkyu no shinpo, 2023
The antibody against myelin oligodendrocyte glycoprotein (MOG) has been identified for its association with several clinical phenotypes including acute or multiphasic disseminated encephalomyelitis, optic neuritis, NMOSD, and brainstem or cerebral cortical encephalomyelitis, and now generally called MOG associated disorders (MOGAD).
openaire   +1 more source

Myelin Oligodendrocyte Glycoprotein (MOG)

2014
Christopher Linington   +3 more
openaire   +1 more source

Preretinal Hemorrhage in Myelin Oligodendrocyte Glycoprotein–Associated Disease

Ophthalmology Retina, 2023
Rasika Sudharshan   +2 more
openaire   +2 more sources

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