Results 231 to 240 of about 300,317 (388)
Advanced Science, EarlyView.Macrophages infiltrate the spinal cord post‐injury, decreasing over time. Microglia phagocytose myelin debris, increasing lipid accumulation. Macrophage deletion improves outcomes, while microglial deletion worsens them. The LD+ microglia subtype shows abnormal Pparg signaling.
Mingran Luo +17 more
wiley +1 more source
Dual Stages of Alcohol-Related Cerebral White Matter Degeneration Reviewed: Early-Stage Stress/Neuroinflammation Versus Late-Stage Impaired Insulin/IGF Signaling Through Akt-mTOR-Review. [PDF]
ASN Neurode la Monte SM, Sutherland G.
europepmc +1 more source
Immunologic Properties of the Main Encephalitogenic Peptide from the Basic Protein of Human Myelin [PDF]
, 1970 Vanda A. Lennon +2 more
openalex +1 more source
Advanced Science, EarlyView.This study systematically explores the action mechanism of Pon3 and its regulatory targets in spinal cord injury (SCI). It demonstrates that Dnmt1 regulates Pon3 expression by modulating methylation levels, thereby inhibiting S1PR1‐mediated pyroptosis and improving SCI prognosis.
Birong Peng +8 more
wiley +1 more source
Chronic cerebral hypoperfusion-induced myelin loss in normal-appearing white matter correlates with cognitive decline: insights from moyamoya disease. [PDF]
Alzheimers Dement (N Y)Yu X +6 more
europepmc +1 more source
Advanced Science, EarlyView.Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan +9 more
wiley +1 more source
Tissue-type plasminogen activator expression by endothelial cells and oligodendrocytes is required for proper CNS myelination. [PDF]
Acta Neuropathol CommunDelaunay-Piednoir B +8 more
europepmc +1 more source