Results 231 to 240 of about 188,742 (365)

Loss of oligodendrocyte ErbB receptor signaling leads to hypomyelination, reduced density of parvalbumin‐expressing interneurons, and inhibitory function in the auditory cortex

open access: yesGlia, Volume 71, Issue 2, Page 187-204, February 2023., 2023
Main Point Loss of oligodendrocyte ErbB receptor signaling leads to A1 hypomyelination, reduced PV expression and density of PV+ neurons and synapses, hypoconnectivity of inhibitory circuits and shift of the E/I balance towards excitation. Abstract For a long time, myelin was thought to be restricted to excitatory neurons, and studies on dysmyelination
Beatriz C. Borges   +4 more
wiley   +1 more source

Addendum: Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease. [PDF]

open access: yesNat Neurosci
Schäffner E   +26 more
europepmc   +1 more source

Defining the pig microglial transcriptome reveals its core signature, regional heterogeneity, and similarity with human and rodent microglia

open access: yesGlia, Volume 71, Issue 2, Page 334-349, February 2023., 2023
Main Points Defined a pig microglial transcriptome signature comprising 239 genes. Demonstrated regional variance in the pig microglial transcriptome across the brain. Revealed similarity of pig microglial gene expression to that of human and mouse microglia.
Barbara B. Shih   +8 more
wiley   +1 more source

Microglia regulate myelin clearance and cholesterol metabolism after demyelination via interferon regulatory factor 5. [PDF]

open access: yesCell Mol Life Sci
Montilla A   +15 more
europepmc   +1 more source

Age-related myelin degradation burdens the clearance function of microglia during aging

open access: yesNature Neuroscience, 2016
S. Safaiyan   +9 more
semanticscholar   +1 more source

A subset of OPCs do not express Olig2 during development which can be increased in the adult by brain injuries and complex motor learning

open access: yesGlia, Volume 71, Issue 2, Page 415-430, February 2023., 2023
Main Points A subset of OPCs do not express Olig2, of which population peaks in the juvenile brain while wanes with age. Plastic changes of the brain by acute injuries or complex motor learning stop the expression of Olig2 in OPCs. Abstract Oligodendrocyte precursor cells (OPCs) are uniformly distributed in the mammalian brain; however, their function ...
Li‐Pao Fang   +7 more
wiley   +1 more source

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