Results 311 to 320 of about 300,317 (388)

Altered Lipid Metabolism in CNS Demyelination and Remyelination Are Key Elements Driving Progressive MS. [PDF]

Int J Mol Sci
Matejuk A, Matejuk S, Offner H, Vandenbark AA.   +3 more
europepmc   +1 more source

Genomics Review of Selective RET Inhibitors Sensitivity in Thyroid Cancer Clinical Trials

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT RET gene is a driver of thyroid cancer (TC) tumorigenesis. The incidence of TC has increased worldwide in the last few decades, both in medullary and follicular‐derived subtypes. Several drugs, including multikinase and selective inhibitors, have been explored.
Sara Gil‐Bernabé, Lucía García‐DeLaFuente, Alejandro García‐Álvarez, Ginesa García‐Rostán, Jaume Capdevila, Jorge Hernando   +5 more
wiley   +1 more source

FBXW7 regulates MYRF levels to control myelin capacity and homeostasis in the adult central nervous system. [PDF]

Nat Commun
Collins HY, Doan RA, Li J, Early JE, Madden ME, Simkins T, Lyons DA, Monk KR, Emery B.   +8 more
europepmc   +1 more source

Cerebral Small Vessel Disease in Older Adults With Olfactory Dysfunction

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Poor vascular health has been associated with age‐related declines in sensory functions, including olfaction. The current study was designed to test the hypothesis that cerebral small vessel disease underlies poor olfactory function due to structural declines in brain regions that support olfaction.
Mark A. Eckert, Judy R. Dubno, Zachary M. Soler, Rodney J. Schlosser   +3 more
wiley   +1 more source

Imaging myelin degradation in ex vivo prefrontal cortex tissue blocks in Alzheimer's disease and chronic traumatic encephalopathy. [PDF]

Alzheimers Dement
Novoseltseva A, Kureli G, Chang S, Yang J, Antinew PD, Chandra A, Berghol S, Spurlock E, McKee AC, Huber B, Wang H, Boas DA, Bigio IJ.   +12 more
europepmc   +1 more source

Studies on encephalitogenic fragments of myelin protein. IV. Synthesis of glycine analogs of tryptophan-containing fragment.

, 1974
Kenji Suzuki, Yusuke Sasaki
openalex   +2 more sources

Dupilumab Initiation for Surgically Refractory Chronic Rhinosinusitis With Nasal Polyps Is Associated With Differential Expression of CLC and Activation of Eicosanoid Pathways

International Forum of Allergy &Rhinology, EarlyView.
Key Points An untargeted transcriptomic analysis provided exploratory insight into key genes and pathways that can be used to help identify patients at risk for surgically refractory chronic rhinosinusitis with nasal polyps (CRSwNP). The Charcot–Leyden crystal gene, periostin and osteopontin‐associated pathways, eicosanoid synthesis pathway, and ...
Christina Dorismond, Rory J. Lubner, Daniel H. Lofgren, Chandler J. Rygalski, Ping Li, Katherine N. Cahill, Suman R. Das, Mason R. Krysinski, Rakesh K. Chandra, Justin H. Turner, Naweed I. Chowdhury   +10 more
wiley   +1 more source

Single-nucleus transcriptomics reveals a distinct microglial state and increased MSR1-mediated phagocytosis as common features across dementia subtypes. [PDF]

Genome Med
Chia SY, Li M, Li Z, Tu H, Lee JWL, Qiu L, Ling J, Reynolds R, Albani S, Tan EK, Ng ASL, Chen J, Zeng L.   +12 more
europepmc   +1 more source

Biocompatibility and healing patterns in experimentally induced canine tibial fractures using Pedicle screw‐Rod external fixation

Animal Models and Experimental Medicine, EarlyView.
This study demonstrates that using a Pedicle screw‐Rod configuration for the external fixation of non‐articular tibial osteotomy aligns well with the principles of biological osteosynthesis, resulting in secondary bone healing characterized by callus formation and neovascularization.
Mohammad Mahdi Gooran, Ramin Mazaheri‐Khameneh, Seyed Mohammad Hashemi‐Asl, Rahim Hobbenaghi   +3 more
wiley   +1 more source

Three-Dimensional Efficient Myelin-Weighted Imaging Utilizing Direct Visualization of Short Transverse Relaxation Time Component (ViSTa). [PDF]

Hum Brain Mapp
Oh SH, Lee G, Lee J.
europepmc   +1 more source