Results 101 to 110 of about 5,959 (257)

Granular cell tumors of the skin contain myelin basic protein

, 1983
Myelin basic protein, a substance found in neural structures, has been demonstrated in cutaneous granular cell tumors using a monoclonal antibody generated against myelin basic protein and an immunoperoxidase method.
Penneys, N S, Adachi, K, Nadji, M, Ziegels-Weissman, J   +3 more
core  

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Designing, Optimization and Construction of Myelin Basic Protein Coding Sequence Binding to the Immunogenic Subunit of Cholera Toxin

Medical Laboratory Journal, 2014
Background and Objectives: Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease. Mucosal feeding of myelin basic protein binding to the cholera toxin B subunit can reduce the intensity of the immune response in MS patients.
N Hashemi, Y Yazdani
doaj  

Effect of enzymatic deimination on the conformation of recombinant prion protein

, 2009
Deimination is the post-translational conversion of arginine residues to citrulline. It has been implicated as a causative factor in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis and more recently, as a marker of ...
Oxley, David, Meersman, Filip, Webster, Judith, Young, Duncan S., Dear, Denise V., Bronstein, Igor, Gill, Andy   +6 more
core  

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Thr94 in bovine myelin basic protein is a second phosphorylation site for 42-kDa mitogen-activated protein kinase (ERK2)

, 2003
Treatment of bovine brain myelin basic protein with 42-kDa mitogen-activated protein kinase [p42 MAPK or extracellular signal-regulated kinase 2 (ERK2)] in the presence of ATP and Mg2+ results in phosphorylation of Thr94 and Thr97.
Hirschberg, Daniel, Jörnvall, Hans, Bergman, Tomas, Rådmark, Olof   +3 more
core  

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Higher levels of myelin phospholipids in brains of neuronal α-Synuclein transgenic mice precede myelin loss

Acta Neuropathologica Communications, 2017
α-Synuclein is a protein involved in the pathogenesis of synucleinopathies, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA).
Jessica Grigoletto, Katharina Pukaß, Ayelet Gamliel, Dana Davidi, Rachel Katz-Brull, Christiane Richter-Landsberg, Ronit Sharon   +6 more
doaj   +1 more source

Acid endopeptidase activity of human myelin, elicited by using exogenous myelin basic protein as enzyme substrate

, 1986
Purified human myelin was incubated with exogenous myelin basic protein (MBP) at pH 4.0 to see if there is acid proteinase activity associated with myelin. Following incubation for 12 h up to 70% of MBP was degraded.
Hans H. Berlet, Berlet, Hans H.
core   +1 more source

Interaction between the C-terminal region of human myelin basic protein and calmodulin: Analysis of complex formation and solution structure [PDF]

, 2008
The myelin sheath is a multilamellar membrane structure wrapped around the axon, enabling the saltatory conduction of nerve impulses in vertebrates. Myelin basic protein, one of the most abundant myelin-specific proteins, is an intrinsically disordered ...
Kursula, P., Päivi Pirilä, Petoukhov, M. V., Dmitri I Svergun, Hayashi, N., Majava, V., Svergun, D. I., Viivi Majava, Petri Kursula, Pirilä, P., Maxim V Petoukhov, Nobuhiro Hayashi   +11 more
core   +1 more source