Results 311 to 320 of about 212,147 (360)
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Myelin Basic Protein

Scandinavian Journal of Immunology, 1982
Our attention was first directed to a study of myelin proteins because of our interest in the induction of experimental allergic encephalomyelitis (EAE) and the fact that Kabat et al. (11) and Morgan (26) had reported that white matter was more encephalitogenic than gray matter.
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Enzyme Immunoassay of the Myelin Basic Protein

Journal of Neurochemistry, 1982
Abstract: An enzyme immunoassay using a double‐antibody solid‐phase technique for myelin basic protein (MBP) has been developed. Antisera were prepared by immunizing rabbits with the purified MBP from chick brain. The conjugation of MBP with horseradish peroxidase was performed by the periodate oxidation method in triethanolamine‐acetate buffer (pH 8 ...
N. Kato   +3 more
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Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity.

Science, 1985
Amino acid sequence homology was found between viral and host encephalitogenic protein. Immune responses were then generated in rabbits by using the viral peptide that cross-reacts with the self protein.
R. Fujinami, M. Oldstone
semanticscholar   +1 more source

Localization of basic proteins in human myelin

Journal of Neuroscience Research, 1993
AbstractThe myelin basic protein (MBPs) represent a family of proteins (charge isomers) which account for 35% of the total myelin protein. Localization studies have been inconclusive because MBP is not a single protein. Antibodies obtained by injection of MBP into animals recognized all members of the MBP family.
C. A. Ackerley   +2 more
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Encephalitogenic Epitopes of Myelin Basic Protein

1989
Etude des determinants antigeniques de la proteine basique myeline capable d'induire une encephalomyelite allergique.
Robert B. Fritz, Dale E. McFarlin
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T-cell recognition of myelin basic protein

Immunology Today, 1991
Multiple sclerosis is a chronic inflammatory disease of the central nervous system which has been hypothesized to be autoimmune in nature. To test whether this is the case, Kai Wucherpfennig and colleagues have developed a set of criteria that must be met to satisfy the hypothesis.
Kai W. Wucherpfennig   +2 more
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Myelin Basic Protein

1981
Myelin basic protein (MBP) has engaged the attention of molecular and cellular immunologists during the past decade because of its implication in the induction of the autoimmune disease experimental allergic encephalomyelitis (EAE) of the central nervous system (CNS).
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Isolation of Myelin Basic Proteins

1974
The history of basic protein in myelin from the central nervous system (CNS) is closely involved with the laboratory disease known as experimental allergic encephalomyelitis (EAE; Alvord, 1970). EAE was shown to be an autoimmune disease when Rabat et al.
P. R. Carnegie, Peter R. Dunkley
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Quantitation of myelination and demyelination by the measurement of myelin basic protein by ELISA

Journal of the Neurological Sciences, 1986
Utilizing a competitive inhibition enzyme-linked immunosorbent assay (ELISA) we measured the amount of myelin basic protein (MBP) in brain, liver, and kidney of newborn mouse and compared these values with myelinated cerebellar explant cultures under various conditions.
J. Wang   +4 more
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Myelin basic protein and myelin protein 2 act synergistically to cause stacking of lipid bilayers.

Biochemistry, 2010
Saltatory conduction of nerve impulses along axonal membranes depends on the presence of a multilayered membrane, myelin, that wraps around the axon. Myelin basic protein (MBP) and myelin protein 2 (P2) are intimately involved in the generation of the ...
S. Suresh   +4 more
semanticscholar   +1 more source

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