Results 181 to 190 of about 331,716 (264)

Clinical Development of Therapies for Charcot–Marie–Tooth Disease: Recommendations for Trial Design, Endpoints, and Regulatory Pathways

open access: yesJournal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.
ABSTRACT Charcot–Marie–Tooth disease (CMT) encompasses a heterogeneous group of inherited peripheral neuropathies. Despite being the most common genetic neurological condition, individual CMT subtypes are rare, presenting unique challenges for therapeutic development.
Charles K. Abrams   +24 more
wiley   +1 more source

Individual neuronal subtypes control initial myelin sheath growth and stabilization. [PDF]

open access: yesNeural Dev, 2020
Nelson HN   +9 more
europepmc   +1 more source

Molecular Mediators Associated With Myelination, Demyelination, and Remyelination in the Peripheral Nervous System

open access: yesJournal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.
ABSTRACT The peripheral nervous system (PNS) is responsible for innervating all regions of the body outside of the central nervous system (CNS), the latter consisting of the brain, spinal cord, and optic nerves. While myelin is an essential component for the efficient functioning of both CNS and peripheral nerve cells, it is particularly important for ...
Kathleen Margaret Hagen   +1 more
wiley   +1 more source

Structural characterization of the human cerebral myelin sheath by small angle x-ray scattering

open access: yes, 2008
Myelin is a multi-lamellar membrane surrounding neuronal axons and increasing their conduction velocity. When investigated by small-angle x-ray scattering (SAXS), the lamellar quasi-periodical arrangement of the myelin sheath gives rise to distinct peaks,
Tartari A   +5 more
core  

Acral Fibrochondromyxoid Tumor: Diagnostic Challenges and Multimodal Characterization in a Hand Mass Case

open access: yesPathology International, Volume 76, Issue 9, September 2026.
Histological morphology of an acral fibrochondromyxoid tumor, low power magnification shows the tumor appeared as a clearly defined nodule. The tumor was divided into nodular structures by fibrous septa, chondrocyte‐like tumor cells were embedded within the abundant chondromyxoid stroma, and most cells exhibited a haphazard distribution. ABSTRACT Acral
Liying Zhang   +4 more
wiley   +1 more source

Use of the IlluminOss Photodynamic Bone Stabilisation System Following Stereotactic Body Radiation Therapy for Limb‐Sparing in Six Dogs With Presumptive Appendicular Osteosarcoma

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 3, Page 611-620, September 2026.
ABSTRACT Osteosarcoma is the most common primary bone tumour in dogs, with approximately 75% of cases occurring in the appendicular skeleton. Standard‐of‐care therapy consists of limb amputation followed by carboplatin chemotherapy. A minority of dogs have limb‐sparing treatments including stereotactic body radiation therapy (SBRT) or surgery. SBRT has
Emily A. Pope   +6 more
wiley   +1 more source

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