Results 221 to 230 of about 48,712 (325)

Quantitative T1 is sensitive to cortical remyelination in multiple sclerosis: A postmortem MRI study

open access: yesBrain Pathology, Volume 35, Issue 5, September 2025.
In a post‐mortem study using multiparametric qMRI of whole fixed human brains from people with multiple sclerosis (pwMS), we found evidence that quantitative T1 (qT1) is sensitive to remyelination in the cortex. In contrast, QSM and radial diffusivity were affected by cortical pathology independently of remyelination. Our data suggest that qT1 could be
Riccardo Galbusera   +14 more
wiley   +1 more source

Nervonic acid, a long chain monounsaturated fatty acid, improves mitochondrial function in adrenomyeloneuropathy fibroblasts

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 17, Page 4134-4146, September 2025.
Abstract Background and Purpose Nervonic acid plays a vital role in maintaining normal brain and neuronal function. Nervonic acid has gained increasing attention because of its potential neuroprotective and anti‐inflammatory properties. Nonetheless, the beneficial effects of nervonic acid are yet to be fully investigated. Adrenomyeloneuropathy (AMN), a
Chenxu Li   +2 more
wiley   +1 more source

Mitochondrial Trifunctional Protein Deficiency due to HADHA Variants Masquerading as Charcot–Marie–Tooth Disease

open access: yesJournal of the Peripheral Nervous System, Volume 30, Issue 3, September 2025.
ABSTRACT Background and Aims Mitochondrial trifunctional protein deficiency (MTPD) is an inherited disorder of fatty acid β‐oxidation caused by mutations in HADHA or HADHB genes. It typically presents with cardiomyopathy or hepatic failure in early childhood; however, it may rarely present in adulthood with the neuromyopathic form.
Farkhanda Qaiser   +6 more
wiley   +1 more source

The Vertebral Column of Flatfish: A Review

open access: yesReviews in Aquaculture, Volume 17, Issue 4, September 2025.
ABSTRACT Flatfish (Pleuronectiformes) encompass fascinating fish species known for their high gastronomical value, rearing performances, and market prices, which attract both economic and scientific interest. Despite these attributes, flatfish exhibit unique morphological, developmental, and biological features, as well as distinctive swimming ...
A. M. de Azevedo   +5 more
wiley   +1 more source

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