Results 221 to 230 of about 232,901 (341)

Depletion of Microglia Increases Cortical Oligodendrocyte Density During Remyelination

open access: yesGlia, Volume 74, Issue 3, March 2026.
Cuprizone demyelination induces transient reactive states in deep cortical microglia (MG) through early recovery. Depleting MG in recovery increases the number of deep cortical mature/pre‐myelinating oligodendrocytes. Deep cortical reactive MG reduce oligodendrocyte density after demyelination.
Hannah Katherine Loo   +5 more
wiley   +1 more source

Individual neuronal subtypes control initial myelin sheath growth and stabilization. [PDF]

open access: yesNeural Dev, 2020
Nelson HN   +9 more
europepmc   +1 more source

Protective effect of miconazole on rat myelin sheaths following premature infant cerebral white matter injury

open access: diamond, 2018
Xuewen Su   +10 more
openalex   +2 more sources

Internalization of Exogenous Myelin by Oligodendroglia Promotes Lineage Progression

open access: yesGlia, Volume 74, Issue 3, March 2026.
Oligodendroglia internalize extracellular myelin debris in vitro and in vivo. Internalized myelin modulates lipid metabolism and lipid droplet formation. Myelin‐derived signals promote oligodendroglial proliferation and lineage progression. ABSTRACT Oligodendrocytes, traditionally recognized for their role in central nervous system myelination, have ...
Carla Peiró‐Moreno   +7 more
wiley   +1 more source

CDC42‐Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity

open access: yesGlia, Volume 74, Issue 3, March 2026.
CDC42‐effector proteins 1/2 are present in CNS myelin. They facilitate the higher order structure of myelin septin filaments. Their loss impairs septin‐dependent scaffolding of myelin. Myelin outfoldings do not cause secondary neuropathology per se. ABSTRACT The regular structure of CNS myelin requires specialized structural proteins, including septin ...
Sophie Hümmert   +14 more
wiley   +1 more source

CNS Myelin Sheath Lengths Are an Intrinsic Property of Oligodendrocytes

open access: yesCurrent Biology, 2015
Marie E Bechler   +2 more
semanticscholar   +1 more source

Lactate Dehydrogenase Inhibition Reverts the Fatty Acid‐Induced Neurotoxic Phenotype of Astrocytes

open access: yesGlia, Volume 74, Issue 3, March 2026.
ALS models display increased LD accumulation. LD accumulation is linked to a neurotoxic phenotype in astrocytes. Lactate dehydrogenase inhibition reverts LD accumulation in ALS astrocytes. ABSTRACT Astrocytes are central to lipid metabolism in the central nervous system.
Daniel Esteve   +5 more
wiley   +1 more source

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