Results 101 to 110 of about 43,839 (265)
Abstract Compiling trait information promotes discovery and innovation in using trait‐based approaches in ecology. Various zooplankton trait datasets are stored in unlinked data repositories, in diverse data structures, and have varying levels of complexity.
Patrick R. Pata, Brian P. V. Hunt
wiley +1 more source
Therapeutic laquinimod treatment decreases inflammation, initiates axon remyelination, and improves motor deficit in a mouse model of multiple sclerosis. [PDF]
BackgroundTherapeutic strategies that induce effective neuroprotection and enhance intrinsic repair mechanisms are central goals for future treatment of multiple sclerosis (MS), as well as other diseases.
Hannsun, Gemmy+9 more
core
Prenatal Brain Abnormalities in Sodium‐Dependent Multivitamin Transporter Deficiency
ABSTRACT In treatable neurometabolic disorders, early diagnosis and prompt initiation of treatment are key to improved survival and outcomes. Biallelic variants in SLC5A6 cause sodium‐dependent multivitamin transporter deficiency (OMIM # 618973), which is treatable with high‐dose pantothenic acid, biotin, and alpha lipoic acid.
Eri Ogawa+2 more
wiley +1 more source
Cell vibron polariton in the myelin sheath of nerve [PDF]
Polaritons are arousing tremendous interests in physics and material sciences for their unique and amazing properties, especially including the condensation, lasing without inversion and even room-temperature superfluidity. Herein, we propose a cell vibron polariton (cell-VP): a collectively coherent mode of a photon and all phospholipid molecules in a
arxiv
Definition of a family of tissue-protective cytokines using functional cluster analysis: a proof-of-concept study [PDF]
The discovery of the tissue-protective activities of erythropoietin (EPO) has underlined the importance of some cytokines in tissue-protection, repair, and remodeling.
Annenkov, Alexander+4 more
core +3 more sources
Accelerated Cellular Senescence in Progressive Multiple Sclerosis: A Histopathological Study
Objective The neurodegenerative processes driving the build‐up of disability in progressive multiple sclerosis (P‐MS) have not been fully elucidated. Recent data link cellular senescence (CS) to neurodegeneration. We investigated for evidence of CS in P‐MS and sought to determine its pattern.
Dimitrios Papadopoulos+8 more
wiley +1 more source
Intrinsic dynamical fluctuations of PNS myelin [PDF]
The ultrastructure fluctuations and complex dynamics of the multi-layered membrane structure of myelin are fundamental for understanding and control its formation process and its degeneration and repair in neurological diseases such as multiple sclerosis (MS).
arxiv
A BIOCHEMICAL AND MORPHOLOGIC STUDY OF MYELINATION AND DEMYELINATION [PDF]
Guido Majno, Manfred L. Karnovsky
openalex +1 more source
At low levels of B12, specifically when bound to transcobalamin for cellular uptake, evidence of slower conductivity in the brain could point toward impaired myelin. At high levels of B12, specifically when bound to the biologically inert transport protein haptocorrin, biomarkers of neurodegeneration appear in the serum, indicating neuroaxonal injury ...
Alexandra Beaudry‐Richard+22 more
wiley +1 more source
White matter microstructure and longitudinal relaxation time anisotropy in human brain at 3 and 7 T
White matter (WM) with high structural anisotropy T1 shows angular dependency on B0. At 3T, a T1 peak at 54° and flat baseline across 0° and 90° are observed in WM [Panel A, T1 as a function of fibre‐to‐filed angle (q)]. At 7T, the T1 peak is centred at 40°.
Risto A. Kauppinen+4 more
wiley +1 more source