Results 111 to 120 of about 43,839 (265)

The signal synchronization function of myelin [PDF]

open access: yesarXiv
The myelinated axons are widely present in both central and peripheral nervous systems. Its unique compact spiraling structure poses significant challenges to understanding its biological functions and developmental mechanisms. Conventionally, myelin is considered as an insulating layer to achieve saltatory conduction for the enhancement of the neural ...
arxiv  

Convolutional Neural Networks for Estimation of Myelin Maturation in Infant Brain [PDF]

open access: yesarXiv, 2019
Myelination plays an important role in the neurological development of infant brain and MRI can visualize the myelination extension as T1 high and T2 low signal intensity at white matter. We tried to construct a convolutional neural network machine learning model to estimate the myelination. Eight layers CNN architecture was constructed to estimate the
arxiv  

Mapping Molecular Pathways of Multiple Sclerosis: A Gene Prioritization and Network Analysis of White Matter Pathology Transcriptomics

open access: yesAnnals of Neurology, EarlyView.
Objectives Rapid advances in transcriptomics have driven efforts to identify deregulated pathways in multiple sclerosis (MS) tissues, though many detected differentially expressed genes are likely false positives, with only a small fraction reflecting actual pathological events. Robust, integrative methods are essential for accurately understanding the
Gianmarco Abbadessa   +11 more
wiley   +1 more source

A diffusion MRI model for random walks confined on cylindrical surfaces: Towards non-invasive quantification of myelin sheath radius [PDF]

open access: yes
Quantifying the myelin sheath radius of myelinated axons in vivo is important for understanding, diagnosing, and monitoring various neurological disorders. Despite advancements in diffusion MRI (dMRI) microstructure techniques, there are currently no models specifically designed to estimate myelin sheath radii.
arxiv   +1 more source

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