Clinical and genetic landscape of epilepsies with absence seizures and single‐gene etiology
Epilepsia, EarlyView.Abstract Objective To characterize the clinical, electroencephalographic, and genetic features of epilepsies featuring absence seizures within monogenic etiology, highlighting the diagnostic, treatment and prognostic implications. Methods We conducted a retrospective, multicenter study including patients with monogenic epilepsies and ...
Simona Balestrini +50 more
wiley +1 more source
STAG2 promotes the myelination transcriptional program in oligodendrocytes
, 2022 Ningyan Cheng +5 more
openalex +1 more source
Olig2‐specific loss‐of‐function Slc35a2 results in hypomyelination and spontaneous seizures
Epilepsia, EarlyView.Abstract Objective Malformations of cortical development represent major causes of drug‐resistant epilepsy, with mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy recognized as a distinct pathological entity. Pathogenic X‐linked SLC35A2, encoding the uridine diphosphate–galactose transporter, has been implicated ...
Tiffany M. Bartel +6 more
wiley +1 more source
Aligned piezoelectric fibrous scaffolds for prevention of traumatic neuroma formation. [PDF]
Front Bioeng BiotechnolChen Y, Gu X, Zang H, Wang C, Li G.
europepmc +1 more source
Prolactin Receptor Deficiency Promotes Hypomyelination in White Matter Tracts During Postnatal Central Nervous System Maturation in Mice. [PDF]
GliaProlactin action is essential for proper myelination of white matter tracts during neonatal and prepubertal stages in mice. Lack of prolactin receptor (Prlr−/−) signaling leads to hypomyelination and impaired locomotor function. ABSTRACT A large wave of myelination in the central nervous system (CNS) of mammals occurs during postnatal development ...
Ocampo-Ruiz AL +12 more
europepmc +2 more sources
The technical and practical implementation of fundus photography in equids
Equine Veterinary Education, EarlyView.Summary Background Fundus photography is an important diagnostic tool in human and veterinary medicine. Advances in research are increasing its accessibility in human medicine. However, there is a lack of studies on modern fundus photography in animals, particularly in horses. Objectives To assess the use of a portable fundus camera developed for human
I. Vierling, B. Wollanke, V. Franzen
wiley +1 more source
Wrap it up: myelination of transplanted neurons for repair. [PDF]
Front Cell NeurosciMartínez-Reza MF, Götz M.
europepmc +1 more source
Acute Intermittent Hypoxia Exerts Beneficial Effects and Promotes Repair in Male Mice in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis. [PDF]
GliaAcute intermittent hypoxia is a novel, noninvasive therapy that shows promising and similar beneficial repair and remyelination following demyelination in male experimental autoimmune encephalomyelitis, as was previously shown in female mice. ABSTRACT Multiple sclerosis (MS) affects women more frequently than men, but the disease progresses more ...
Tokarska N +6 more
europepmc +2 more sources