Results 191 to 200 of about 61,218 (243)
Tracking early cognitive decline in preclinical AD with brain MRI similarity
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION Early detection of neuroanatomical changes in preclinical Alzheimer's disease (AD) is critical for timely intervention. However, conventional magnetic resonance imaging (MRI) and fluid biomarkers often lack sensitivity to subtle structural alterations in early disease stages. METHODS To identify early brain alterations, we applied
Jiawei Sun +6 more
wiley +1 more source
The neuromodulatory fragility hypothesis of Alzheimer's disease pathogenesis
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract Sporadic Alzheimer's disease (AD) is associated with numerous risk factors, yet its precise cause remains unclear. Here, we describe a novel framework for AD pathogenesis, whereby diverse risk factors converge on neuromodulatory subcortical systems to confer AD risk or resilience.
Alfie Wearn +4 more
wiley +1 more source
Anti-TLR2 immunotherapy modulates neuron-to-oligodendrocyte propagation of α-synuclein in mouse and human models. [PDF]
Nat CommunBae EJ +11 more
europepmc +1 more source
Oxysterol signaling in the central nervous system: cellular mechanisms and implications for neurodegeneration. [PDF]
Front Mol NeurosciRicci RP, Foo CX, Ronacher K, Cullen CL.
europepmc +1 more source
Prenatal Exposure to Tobacco Smoke and Vaping Aerosols: Mechanisms Disrupting White-Matter Formation. [PDF]
ToxicsBeltran-Castillo S +2 more
europepmc +1 more source
Internalization of Exogenous Myelin by Oligodendroglia Promotes Lineage Progression. [PDF]
GliaPeiró-Moreno C +7 more
europepmc +1 more source
Perinatal Fluoxetine Exposure Has No Major Effect on Myelin-Associated Glycoprotein and Myelin Basic Protein Levels in Auditory Brain Regions. [PDF]
Biology (Basel)Jagersma JD +4 more
europepmc +1 more source