Results 221 to 230 of about 43,839 (265)

Human Brain Myelination from Birth to 4.5 Years

, 2008
Bérengère Aubert-Broche, Vladimir Fonov, Ilana R. Leppert, G. Bruce Pike, D. Louis Collins   +4 more
openalex   +1 more source

Cell type mapping of mild malformations of cortical development with oligodendroglial hyperplasia in epilepsy using single‐nucleus multiomics

Epilepsia, EarlyView.
Abstract Objective Mild malformations of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) are brain lesions associated with focal epilepsy and characterized by increased oligodendroglial density, heterotopic neurons, and hypomyelination in the white matter.
Isabella C. Galvão, Manuela Lemoine, Ludmyla Kandratavicius, Clarissa L. Yasuda, Marina K. M. Alvim, Enrico Ghizoni, Ingmar Blümcke, Fernando Cendes, Fabio Rogerio, Iscia Lopes‐Cendes, Diogo F. T. Veiga   +10 more
wiley   +1 more source

Transfer RNA and small molecule therapeutics for aminoacyl‐tRNA synthetase diseases

The FEBS Journal, EarlyView.
Aminoacyl‐tRNA synthetases catalyze the ligation of a specific amino acid to a cognate tRNA—a reaction that lays the foundations for deciphering the genetic code. Pathogenic alleles in these synthetases can lead to dominant or recessive disorders, for which little or no disease‐specific treatments exist.
Tristan N. Samuels, Fanqi Wu, Maria Mahmood, Wajd A. Abuzaid, Nancy Sun, Angelica Moresco, Victoria M. Siu, Patrick O'Donoghue, Ilka U. Heinemann   +8 more
wiley   +1 more source

On the synergy between myelin proteins P0, MBP, and P2 in peripheral nerve major dense line formation

The FEBS Journal, EarlyView.
Myelin is a multilayered proteolipid membrane in the nervous system. The lipid membranes are held together by specific proteins, and here, we studied three such proteins—P0, MBP, and P2. Our experiments show that the three proteins may act in synergy at the molecular level, while they also compete for lipid membrane surface binding.
Oda C. Krokengen, Arne Raasakka, Martin Berg Klenow, Antara Pal, Øystein Hetland, Anna Mularski, Salla Ruskamo, Jan Skov Pedersen, Adam Cohen Simonsen, Petri Kursula   +9 more
wiley   +1 more source

miR-23regulation of lamin B1 is crucial for oligodendrocyte development and myelination

, 2009
Shuting Lin, Ying‐Hui Fu
openalex   +2 more sources

Hyperhidrosis: don't sweat it

Internal Medicine Journal, EarlyView.
Abstract Hyperhidrosis is an under‐reported and under‐treated condition that causes significant patient morbidity. Secondary causes require consideration, but the vast majority of cases are idiopathic. The condition is encountered by a range of clinicians, including neurologists, dermatologists and endocrinologists, and it pays to be familiar with the ...
Mitchell J. Lycett, Karl Ng
wiley   +1 more source

Diel Vertical Migration Shapes North Atlantic Copepod Bioregions

Journal of Biogeography, EarlyView.
ABSTRACT Aim Assessing the influence of diel vertical migration (DVM) on biogeographic patterns to improve the macroecological characterisation of the structure and function of zooplankton communities. Location North Atlantic Ocean and adjacent seas. Taxon Marine copepod species.
Marion Vilain, Eric Goberville, Dorothée Vincent, Fabio Benedetti, Frédéric Olivier   +4 more
wiley   +1 more source

Mind the GAPS: Glia associated with psychological stress

Journal of Neuroendocrinology, EarlyView.
Abstract Glial cells are an integral component of the nervous system, performing crucial functions that extend beyond structural support, including modulation of the immune system, tissue repair, and maintaining tissue homeostasis. Recent studies have highlighted the importance of glial cells as key mediators of stress responses across different organs.
Niklas Blank, Molly Weiner, Shaan Patel, Sarah Köhler, Christoph A. Thaiss   +4 more
wiley   +1 more source

Early testosterone exposure during development advances myelination and affects neurogenesis of the vocal control motor path in male zebra finches (Taeniopygia guttata)

Journal of Neuroendocrinology, EarlyView.
Abstract Birdsong learning and production is mediated through a vocal control circuit that exhibits ubiquitous and profound sex differences. In zebra finches (Taeniopygia guttata) only males sing, and sex differences in both neuroanatomy and myelination of this circuit emerge during the first 3 months of life as song learning is taking place.
Adriana Diez, Kevin G. Young, Scott A. MacDougall‐Shackleton   +2 more
wiley   +1 more source

MRI‐based surrogates of brain clearance in narcolepsy type 1

Journal of Sleep Research, EarlyView.
Summary Brain clearance involves the drainage of waste molecules from the brain, a process that is suggested to be amplified during sleep. Recently proposed MRI‐based methods attempt to approximate human brain clearance with surrogate measures. The current study aimed to explore whether two brain clearance surrogates are altered in narcolepsy.
Eva M. van Heese, Jari K. Gool, Gert Jan Lammers, Ysbrand D. van der Werf, Matthias J. P. van Osch, Rolf Fronczek, Lydiane Hirschler   +6 more
wiley   +1 more source