Myeloid-lymphoid leukemia protein

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Aberrant expression of SLAMF6 constitutes a targetable immune escape mechanism in acute myeloid leukemia

Nature Cancer
Immunotherapy has shown limited success in acute myeloid leukemia (AML), indicating an incomplete understanding of the underlying immunoregulatory mechanisms. Here we identify an immune evasion mechanism present in 60% of AML cases, wherein primitive AML
Carl Sandén +16 more
semanticscholar +1 more source

Evaluation of some genes and proteins involved in apoptosis on human chronic myeloid leukemia cells (K562 cells) by datura innoxia leaves aqueous extract

Journal of Biomolecular Structure and Dynamics, 2019
Datura innoxia (D. innoxia) has an extensive usage in traditional medicine and can also be used for intervention therapy in order to treat cancer. Despite of accomplishing some researches on D.
Elham Chamani +5 more
semanticscholar +1 more source

Asciminib for relapsed or refractory Philadelphia chromosome–positive acute lymphoblastic leukemia

Blood Advances
Asciminib (ASC) is an allosteric inhibitor of BCR::ABL1 that binds the myristoylation site of the ABL1 protein. We report the use of ASC in relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) and lymphoid blast crisis of ...
M. Chanut +28 more
semanticscholar +1 more source

Effect of Clathrin Assembly Lymphoid Myeloid Leukemia Protein Depletion on Clathrin Coat Formation