Results 31 to 40 of about 919,731 (432)
Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma
Science, 2021 Getting around the blood–brain barrier The meninges comprise three membranes that surround and protect the central nervous system (CNS). Recent studies have noted the existence of myeloid cells resident there, but little is known about their ontogeny and
A. Cugurra +16 more
semanticscholar +1 more source
Role of the bone morphogenic protein pathway in developmental haemopoiesis and leukaemogenesis [PDF]
, 2016 Myeloid leukaemias share the common characteristics of being stem cell-derived clonal diseases, characterised by excessive proliferation of one or more myeloid lineage.
Toofan, Parto, Wheadon, Helen
core +1 more source
Murine Liver Myeloid Cell Isolation Protocol
Bio-Protocol, 2015 In homeostasis, the liver is critical for the metabolism of nutrients including sugars, lipids, proteins and iron, for the clearance of toxins, and to induce immune tolerance to gut-derived antigens.
Benoit Stijlemans +8 more
doaj +1 more source
eLife, 2020 Cancer immunotherapy by immune checkpoint blockade has proven its great potential by saving the lives of a proportion of late stage patients with immunogenic tumor types.
Ana Rita Pombo Antunes +5 more
doaj +1 more source
Congenital leukemia cutis in an infant
Indian Journal of Paediatric Dermatology, 2022 Background: The infiltration of neoplastic leukocytes or their progenitors into the epidermis, dermis, or subcutis, resulting in clinically evident cutaneous lesions, is known as leukemia cutis.
Carol Lobo, J P Prathibha
doaj +1 more source
Acute myeloid leukemia: current progress and future directions
Blood Cancer Journal, 2021 Progress in the understanding of the biology and therapy of acute myeloid leukemia (AML) is occurring rapidly. Since 2017, nine agents have been approved for various indications in AML.
H. Kantarjian +8 more
semanticscholar +1 more source
Nature Communications, 2016 Dendritic cells are antigen-presenting cells consisting of distinct subsets originating from different lineages. Here, the authors identify the subsets of dendritic cells populating the tumour tissue in both mice and humans and find they have opposing ...
Damya Laoui +16 more
doaj +1 more source
Purification of Tumor-Associated Macrophages (TAM) and Tumor-Associated Dendritic Cells (TADC)
Bio-Protocol, 2014 Tumors are heterogeneous microenvironments where complex interactions take place between neoplastic cells and infiltrating inflammatory cells, such as tumor-associated macrophages (TAM) and tumor-associated dendritic cells (TADC).
Damya Laoui +4 more
doaj +1 more source
Acute myelogenous leukemia – current recommendations and approaches in molecular-genetic assessment
Romanian Journal of Internal Medicine, 2022 Acute myelogenous leukemia is a multi-step hematological malignancy, affecting function, growth, proliferation and cell cycle of myeloid precursors.
Yahya Dinnar +3 more
doaj +1 more source
Myeloid-derived suppressor cells as immunosuppressive regulators and therapeutic targets in cancer
Signal Transduction and Targeted Therapy, 2021 Myeloid-derived suppressor cells (MDSCs) are a heterogenic population of immature myeloid cells with immunosuppressive effects, which undergo massive expansion during tumor progression. These cells not only support immune escape directly but also promote
Kai Li +8 more
semanticscholar +1 more source