Results 21 to 30 of about 604,501 (260)

Conservative Management of Presumed Fetal Anemia Secondary to Maternal Chemotherapy for Acute Myeloid Leukemia

American Journal of Perinatology Reports, 2021
Acute myeloid leukemia occurs rarely during pregnancy. When it is diagnosed remote from term, treatment in the form of daunorubicin plus cytarabine induction with consolidative cytarabine is typically undertaken after the first trimester. There is little
Christina M. Nowik, Alina S. Gerrie, Jonathan Wong   +2 more
doaj   +1 more source

Diamonds in the Rough: Harnessing Tumor-Associated Myeloid Cells for Cancer Therapy

Frontiers in Immunology, 2018
Therapeutic approaches that engage immune cells to treat cancer are becoming increasingly utilized in the clinics and demonstrated durable clinical benefit in several solid tumor types.
Emile J. Clappaert, Emile J. Clappaert, Aleksandar Murgaski, Aleksandar Murgaski, Helena Van Damme, Helena Van Damme, Mate Kiss, Mate Kiss, Damya Laoui, Damya Laoui   +9 more
doaj   +1 more source

Macrophage Subsets in Obesity, Aligning the Liver and Adipose Tissue

Frontiers in Endocrinology, 2020
The increasing prevalence of obesity is accompanied by a rising incidence in metabolic syndrome and related pathologies such as non-alcoholic fatty liver disease. Macrophages are hypothesized to play central roles in these diseases, through their role as
Anneleen Remmerie, Anneleen Remmerie, Liesbet Martens, Liesbet Martens, Liesbet Martens, Charlotte L. Scott, Charlotte L. Scott   +6 more
doaj   +1 more source

Adoptive Transfer of Monocytes Sorted from Bone Marrow

Bio-Protocol, 2019
Inflammatory Ly6Chi monocytes can give rise to distinct mononuclear myeloid cells in the tumor microenvironment, such as monocytic myeloid-derived suppressor cells (Mo-MDSC), immature macrophages, M2-like tumor-associated macrophages (TAMs), M1-like TAMs
Damya Laoui, Eva Overmeire, Chloé Abels, Jiri Keirsse, Jo Ginderachter   +4 more
doaj   +1 more source

Hematopoietic stem cells produce intermediate lineage adipocyte progenitors that simultaneously express both myeloid and mesenchymal lineage markers in adipose tissue

Adipocyte, 2021
Some adipocytes are produced from bone marrow hematopoietic stem cells. In vitro studies previously indicated that these bone marrow-derived adipocytes (BMDAs) were generated from adipose tissue macrophage (ATM) that lose their hematopoietic markers and ...
Kathleen M. Gavin, Timothy M. Sullivan, Joanne K. Maltzahn, Jeremy T. Rahkola, Alistair S. Acosta, Wendy M. Kohrt, Susan M. Majka, Dwight J. Klemm   +7 more
doaj   +1 more source

High-Yield Human Induced Pluripotent Stem Cell-Derived Monocytes and Macrophages Are Functionally Comparable With Primary Cells

Frontiers in Cell and Developmental Biology, 2021
Macrophages are pivotal effectors of host immunity and regulators of tissue homeostasis. Understanding of human macrophage biology has been hampered by the lack of reliable and scalable models for cellular and genetic studies.
Di Cui, Alexandra Franz, Sophie A. Fillon, Linda Jannetti, Timo Isambert, Katrin Fundel-Clemens, Heinrich J. Huber, Coralie Viollet, Alexander Ghanem, Akira Niwa, Bernd Weigle, Stefan Pflanz, Stefan Pflanz   +12 more
doaj   +1 more source

Optimization of the indications for allogeneic stem cell transplantation in Acute Myeloid Leukemia based on interactive diagnostic strategies [PDF]

, 2011
The indications for allogeneic stem cell transplantation (SCT) in Acute Myeloid Leukemia (AML) represent a real challenge due to the clinical and genetic heterogeneity of the disorder.
Hartwig, Maite, Zander, Axel R., Haferlach, Torsten, Fehse, Boris, Bacher, Ulrike, Kröger, Nicolaus   +5 more
core   +1 more source

Characteristics of “Tip-DCs and MDSCs” and their potential role in leishmaniasis [PDF]

, 2012
Since the first description of dendritic cells (DCs) by Steinman and Cohn (1973), the myeloid lineage of leukocytes was investigated intensively. Nowadays it is obvious that myeloid cells, especially DCs, are crucial for the adaptive and innate immune ...
Schmid, Maximilian, Anja Kathrin Wege, Maximilian eSchmid, Uwe eRitter, Anja K. Wege, Maximilian Schmid, Uwe Ritter, Ritter, Uwe, Wege, Anja K.   +8 more
core   +1 more source

Acute myelogenous leukemia – current recommendations and approaches in molecular-genetic assessment

Romanian Journal of Internal Medicine, 2022
Acute myelogenous leukemia is a multi-step hematological malignancy, affecting function, growth, proliferation and cell cycle of myeloid precursors.
Yahya Dinnar, Hachmeriyan Mari, Micheva Ilina, Chervenkov Trifon   +3 more
doaj   +1 more source

Myeloid IκBα deficiency promotes atherogenesis by enhancing leukocyte recruitment to the plaques. [PDF]

, 2011
Activation of the transcription factor NF-κB appears to be involved in different stages of atherogenesis. In this paper we investigate the role of NF-κB inhibitor IκBα in atherosclerosis.
Menno P J de Winther, Hofker Marten H., Hofker, Marten H., Rupec Rudolf A., Curfs Danielle M. J., Woezik, J.H.G. (Johannes H.) van, Hoeksema, Marten A., Goossens, P. (Pieter), Rudolf A Rupec, Hoeksema Marten A., Leenen, Pieter J. M., Leenen, P.J.M. (Pieter), Winther, M.P.J. (Menno P.) de, Marion J. J. Gijbels, Leenen Pieter J. M., Hoeksema, M.A. (Marten), Danielle M J Curfs, Pieter J M Leenen, Marten A. Hoeksema, Gijbels, Marion J. J., Vergouwe, Monique N., Gijbels, M. (Marion), Johannes H. G. van Woezik, Rupec, R.A. (Rudolf), Xanthouleas, Sofia, de Winther, Menno P. J., Gijbels Marion J. J., Monique N. Vergouwe, Xanthoulea Sofia, Goossens, Pieter, Curfs, Danielle M. J., Johannes H G van Woezik, Marten H. Hofker, van Woezik, Johannes H. G., Marion J J Gijbels, Xanthoulea, Sofia, Vergouwe, Y. (Yvonne), Xanthoulea, S. (Sofia), van Woezik Johannes H. G., Sofia Xanthoulea, Goossens Pieter, Vergouwe Monique N., Rupec, Rudolf A., Hofker, M.A. (Marten), Curfs, D.M.J. (Danielle M.), Marten A Hoeksema, Marten H Hofker, Pieter J. M. Leenen, Menno P. J. de Winther, Danielle M. J. Curfs, de Winther Menno P. J., Rudolf A. Rupec, Pieter Goossens, Monique N Vergouwe, Hofker, MH, Curfs, DMJ, Rupec, RA, van Woezik, JHG, Vergouwe, MN, Gijbels, MJJ, de Winther, MPJ, Goossens, P, Xanthoulea, S, Hoeksema, MA, Leenen, Pieter   +64 more
core   +2 more sources